Lymph And Immune Flashcards
Functions of lymph system
Return fluid frok tissue soaces to blood
Absord fat fat soluble vitamins from digestive tract
Defense against infection
What dies lymphatuc system contain
Lymphocytes p
Phagocytes
Water electrokytes waste
Where dies kymph system flow
Through venus system
Always moves items to heart never away
Fluid from tissue soace not reabsorbed by blood capillaries it enters the lymohatic system
True
There is no lymph in the cns
Ttue thats why swelling is harder to get rid of there
Flow of lymphv
Lymph capilaries
Ducts(thiracis ducts)
Right and left subclavian veins
Lymph is oumped by heart
False- pumoed by skeletal muscle gravity and interthoracic pressures
Lymoh- Valves present to keep flowing towards ducts so it can ve returned to circ system
Ttue
What are patches of lymph tissue strategically placer to filter lymph as flows through system
Lymoh nodes
Large clusters of lymph nodes calked
Plexis
What are head neck lymoh nodes called
Cervical nodes
Upper extremity and limbs shoulder nodes
Axillary
Groin femoral genitalia lymph nodes
Inguinal
2nd line defense nonsoecific
Phagocytosis
Inflammation fever- histamine released causes redness, heat, swelling, pain. Causes vasodilation
Pyrexia aka fever
Protective proteins- interferon- works against viruses
Complement proteins- circukates inactive .pokes holes in bacteria
Nk cells - works against cancer and microves
What does inflammatory respinse produce
Redness swelling heat pain as a result of vasodilation
Condition of licalized fluid retention and tissue swelliny caused by compromised lymohatic system
Lymphadema
Circukatee inactively there just in case we need it . Pokes hole in bacteria
Complement bacteria
Whennus lymohadema most commonly seen
Node discection. Radiationx removal lymohatif system caused by tx of cancer
Cells work against cancer and mucrobes
Natural born killer cells
Lymphatic tissue located in mucosa partially encapsulated lymph nodes in throat area
Tonsils
Appendix contains what?
Lymohatic nodules
Largest lymohatic organ in body
Spleen
What dies soleen fikter
Blood not lymph fluid
Requires activation by specific antigen has memory for future attacks
- antibody mediated
- Cell mediated
Specific aka adaptive immunity
Immunity based 9n activitybof b lymphocytes
Antibody mediated
4 types T cells
- Killer cells cytoxic cells
- Helper t cells
- Supressor t cells(once battle over)
- Memory t cell (remembers antigen for future attacks)
What percentage are t cells
70-80 %
This immune cell response doesnt involve antibodies. Involves activation of phagocytes antigrn soecific cytotoxix t lymphocytes
Cell mediated
Immunoglobulins aka name
Anti bodies
Why are immunoglobukine aka antibodies made
In response to something specific
What does antibody mediated immunity involve
Protects via antibodies Protects via extra cellular pathogens B cells b lymphocytes Basis of artificial immunity The antibody remains circukating in system. B cells make 2 copies
What does cell mediated protect against
Protects cells by directing against intercellukar pathogens aka macrophages
Some cancers
Tissue rejection
Antigen presentation- body sees something not native to me so it activates t cells
What are protective proteins called
Interferons
What does antibody mediated immunity circulate
Produces circukating antibodies in response to presence of foreign substance and recognize substance upon renewed exposure
What does white pulp do
Cleans blood the same as lymph nodes clean lymph fluid. Lymphatic tissue and lumphocytes
Info 9n red pulp
Venus sinuses filled w blood
Blood cleansed as flows through
Microorganisms destroyed by leaukocytes
Stores blood esoecialoy platelets
Lymphatic organ that is where t cells matures In mediastinum Decreases in size and function Home of lymphocytes Some inactive and some active Active in immune response Secretes hormones
Thymus gland
Formation of antibodies to substances usually not recognized as foreign ex. Peanut butter
Allergic reactions
2 types allergic reactions
Delayed onse- allergy takes abiut 48 hrs to develop
Immediate reactions-need epipen. Pollen drugs
Organ transplant issues?
Tissue or organ rejection
