Lymph Flashcards
Cisterna chyli
Storage of chyle from GI tract
Upper right quadrant
Right subclavian vein
Rest of body except upper right quadrant
Left subclavian vein
How many lymph nodes
700
Clinically important lymph node positions
Neck -cervical
Groin- inguinal
Armpit - axillary
Lymph structure
Kidney shaped
Multiple follicles - germinal centres
Medulla
Main connective tissue - reticulin (collagen 3)
Multiple afferent lymphatic vessel in convex surface
Single efferent lymphatic vessel in concave surface (Hilum)
Feeding artery - leaves via hilum
Drawing vein - leaves via hilum
Follicular dendritic cells
Located in terminal centres
Antigen antibody complexes on dendritic processes
Allow macrophages to engulf pathogen
Proliferation of B cells
Lymphadenopathy
Germinal centres swell with increased number lymphocytes
Cancer meta stiles to afferent lymphatic vessel
Lymphoma
Hodgkins and non - Hodgkins
Malignancy of lymph tissue
Lymphatic organs
Thymus Spleen Appendix Payers patches Tonsils
Thymus
Superior mediastinum
No hilum
Fully function and formed at birth
Involutes when adult - fat
T Cell education from bone marrow derived stem cells
Spleen
Biggest lymphatic organ
Red pulp - stores RBC - destroys old, damaged, defective RBC retrieves Fe from haem
White pulp - lymphatic activity - activates B and T lymphocytes
Removes macromolecular antigens by macrophages
Inferior to diaphragm
Posterior to stomach
Splenomegaly
Enlarged spleen in response to systemic infection
Tonsils
Oropharynx - lingual and palatine tonsils
Nasopharynx - adenoid (pharyngeal tonsils)
Vermiform appendix
Inferior and attached to caecum of ascending colon
Prevents pathogen ingress in GI tract
