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LECTURE WEEKS > LW3 > Flashcards

LW3 Flashcards

1
Q

Causes of myocarditis

A

Viral (coxsachie: heart foot and mouth), Bacterial (meningococcus), Radiation, Drugs

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2
Q

How do fibrinolytics work

A

converts plasminogen to plasmin which breaks down fibrin and so dissolves thrombi

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3
Q

What bleeds do you get in haemophilia?

A

haemarthroses, haematuria, intramuscular , intracranial

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4
Q

Treatment of haemophilias+von willebrand?

A

DDAVP (only in A+vWF), factor concentrates, tranaxemic acid,

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5
Q

Investigations for haemorrhagic disorder

A

FBC, renal function, LFTs, Paraproteins

can also do factor assays, mixing studies etc

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6
Q

Causes of long PT

A

Warfarin, vit K deficiency, liver dysfn, Factor 7 def

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7
Q

Causes of long APTT

A

Haemophilia, von willebrand, Lupus anticoagulant, heparin

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8
Q

PT + APTT pattern in Vit K deficiency

A

^^PT and ^APTT

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9
Q

Causes of acquired bleeding disorders

A

Vit K def, Vit C def (affects collagen synthesis), DIC, Liver disease, acquired haemophilia

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10
Q

Acquired haemophilia pathophys

A

Spontaneous low factor 8 inhibitor which causes a very long APTT confirmed with inhibitor assay

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11
Q

Acquired haemophilia treatment

A

FEIBA, Novoseven, steroids, DDAVP, rituximab

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12
Q

Wiskott Aldrich Syndrome

A

hereditary thrombocytopaenia and eczema

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13
Q

Cause of bacterial endocarditis in neonates and in adults?

A

staph aureus in neonates and strep viridans

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14
Q

Causative organism for myocarditis?

A

adenovirus

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15
Q

Causes of congenital heart disease

A

TORCH, chromosomal abnormalities

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16
Q

Treatment algorithm for HF (ABASI-D)

A
  1. ACE and beta blocker
  2. Aldosterone antagonist
  3. Sacubatril/Valsartan
  4. ICD/Ivabradine
  5. Digoxin + Hydralazine
  6. LVAD
17
Q

Causes of acute heart failure?

A

cardiogenic shock, volume overload, sepsis

18
Q

Criteria for ICD vs CRT

A

No LBBB and narrow QRS: ICD

LBB and wide QRS: CRT

19
Q

What conditions are digoxin contraindicated in?

A

WPW and HOCM

20
Q

How does kawaski affect the heart?

A

Coronary artery aneurysms

21
Q

Chronic heart failure management:

  1. BNP 100-400 NT 400-2000
  2. BNP >400 NT > 2000
A

ECHO in both cases

  1. 6 wk referral
  2. 2 week referral
22
Q

What BNP (and NT) is needed for diagnosing acute heart failure

A

BNP >100 NT>300

23
Q

Antiarrythmic classes (Some Boys Play Catch)

A
  1. Sodium channel blockers: quinidine, lidocaine, flecainide
  2. Beta antagonists: propanolol, metoprolol
  3. Potassium channel Blockers: amiodarone, sotalol
  4. Calcium channel blockers: verapamil

LECTURE WEEKS (5 decks)

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