Luteinizing hormone (LH) Flashcards
Also known as lutropin is a hormone produced by the anterior pituitary gland.
Important markers in diagnosing fertility and menstrual cycle disorders
The release of LH at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Those pulses, in turn, are subject to the estrogen feedback from the gonads.
Luteinizing hormone (LH)
In the female, an acute rise of LH – the LH surge – triggers
ovulation
In the male, where LH had also been called
It stimulates ______cell production of testosterone
Interstitial Cell Stimulating Hormone (ICSH); Leydig
LH levels are normally low during childhood and, in women, high after __________.
menopause
Persistently high LH levels are indicative of situations where the normal restricting feedback from the gonad is absent, leading to a pituitary production of both___________. While this is typical in the menopause, it is abnormal in the reproductive years.
LH and FSH
High LH levels may be a sign of:
- Premature menopause
- Gonadal dysgenesis, Turner syndrome
- Castration
- Swyer syndrome
- Polycystic Ovary Syndrome
- Testicular failure
Diminished secretion of LH can result in failure of gonadal function (hypogonadism). This condition is typically manifest in males as failure in production of normal numbers of sperm. In females, ____________is commonly observed.
amenorrhea
Conditions with very low LH secretions are:
- Kallmann syndrome
- Hypothalamic suppression
- Hypopituitarism
- Eating disorder
- Hyperprolactinemia
- Gonadotropin deficiency