Luteinizing hormone (LH) Flashcards

1
Q

 Also known as lutropin is a hormone produced by the anterior pituitary gland.
 Important markers in diagnosing fertility and menstrual cycle disorders
 The release of LH at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone (GnRH) from the hypothalamus. Those pulses, in turn, are subject to the estrogen feedback from the gonads.

A

Luteinizing hormone (LH)

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2
Q

In the female, an acute rise of LH – the LH surge – triggers

A

ovulation

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3
Q

 In the male, where LH had also been called
 It stimulates ______cell production of testosterone

A

Interstitial Cell Stimulating Hormone (ICSH); Leydig

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4
Q

LH levels are normally low during childhood and, in women, high after __________.

A

menopause

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5
Q

Persistently high LH levels are indicative of situations where the normal restricting feedback from the gonad is absent, leading to a pituitary production of both___________. While this is typical in the menopause, it is abnormal in the reproductive years.

A

LH and FSH

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6
Q

High LH levels may be a sign of:

A
  1. Premature menopause
  2. Gonadal dysgenesis, Turner syndrome
  3. Castration
  4. Swyer syndrome
  5. Polycystic Ovary Syndrome
  6. Testicular failure
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7
Q

Diminished secretion of LH can result in failure of gonadal function (hypogonadism). This condition is typically manifest in males as failure in production of normal numbers of sperm. In females, ____________is commonly observed.

A

amenorrhea

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8
Q

Conditions with very low LH secretions are:

A
  1. Kallmann syndrome
  2. Hypothalamic suppression
  3. Hypopituitarism
  4. Eating disorder
  5. Hyperprolactinemia
  6. Gonadotropin deficiency
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