Follicle-stimulating hormone (FSH)

Question 1

 It is a hormone synthesized and secreted by gonadotropes in the anterior pituitary gland.
 regulates the development, growth, pubertal maturation, and reproductive processes of the human body. FSH and Luteinizing hormone (LH) act synergistically in reproduction.
 Important markers in diagnosing fertility and menstrual cycle disorders

Answer 1

Follicle-stimulating hormone (FSH)

Question 2

Structure
 FSH is a _________________
 Its structure is similar to those of LH, TSH, and hCG
 The sugar part of the hormone is composed of

Answer 2

glycoprotein
fucose, galactose, mannose, galactosamine, glucosamine, and sialic acid

Question 3

Activity
FSH regulates the development, growth, pubertal maturation, and reproductive processes of the human body.
 In both males and females, FSH stimulates the maturation of ______ cells.
 Like its partner, LH, FSH release at the pituitary gland is controlled by pulses of gonadotropin-releasing hormone (GnRH).

Answer 3

germ

Question 4

Disease states
FSH levels are normally _____ during childhood and, in females, high after ___________.

Answer 4

low; menopause

Question 5

High levels of Follicle-Stimulating Hormone are indicative of situations where the normal restricting feedback from the _______ is absent, leading to an unrestricted pituitary FSH production. Whereas this is _________ in females leading up to and during postmenopause, it is ___________ during the reproductive years.

Answer 5

gonad; normal; abnormal

Question 6

If the FSH level is high during the reproductive years, this may be a sign of:

Answer 6

1. Premature menopause also known as Premature Ovarian Failure
2. Poor ovarian reserve also known as Premature Ovarian Aging
3. Gonadal dysgenesis, Turner syndrome
4. Castration
5. Swyer syndrome
6. Testicular failure.

Question 7

also known as Premature Ovarian Failure

Answer 7

Premature menopause

Question 8

also known as Premature Ovarian Aging

Answer 8

Poor ovarian reserve

Question 9

Diminished secretion of FSH can result in failure of gonadal function (hypogonadism). This condition is typically manifested in males as failure in production of normal numbers of ______. In females, __________of reproductive cycles is commonly observed.

Answer 9

sperm; cessation

Question 10

Conditions with very low FSH secretions are:

Answer 10

1. Polycystic Ovarian Syndrome
2. Polycystic Ovarian Syndrome + Obesity + Hirsutism + Infertility
3. Kallmann syndrome
4. Hypothalamic suppression
5. Hypopituitarism
6. Hyperprolactinemia
7. Gonadotropin deficiency