Lungs in the wild environment Flashcards
What does boyles law state?
At a constant temperature the absolute pressure of a fixed mass of gas is inversely proportional to its volume
P1V1=P2V2
What is an arterial gas embolism?
Gas enters circulation via torn pulmonary veins
Small transpulmonary pressures can lead to AGE
Normally occur within 15 minutes of surfacing
Urgent recompression needed
What is apnoea?
pause in breathing
What is pulmonary oxygen toxicity?
If PiO2 > 0.5 ATA (atmospheric absolute)
100% oxygen leads to symptoms in 12 - 24 hours
Cough, chest tightness, chest pain, shortness
of breath
Also a problem with ITU patients
Normal physiological response to ascent:
Hypoxia leads to..
Hyperventilation at 10000ft altitude
Increases minute ventilation
Lowers PaCO2
Alkalosis initially
Tachycardia
Ascending; PiO2 falls (FiO2 remains constant)
Decreased PAO2
Decreased PaO2
Peripheral chemoreceptors fire (e.g. carotid body)
Activates increased ventilation (VA), reducing PaCO2
Increased PAO2
Increased PaO2
Name 3 high altitude ilnesses
Acute Mountain Sickness
High Altitude Pulmonary oEdema (HAPE)
High Altitude Cerebral Oedema (HACE)
Acute mountain sickness
Recent ascent to over 2500m
Lake Louise score > 3
Must have a headache and one other symptom
Treatment is to descend
High Altitude Pulmonary Oedema
Unacclimatised individuals
Cough, shortness of breath
Rapid ascent above 8000ft (2438m), more common in excercise
2-5 days
Treatments:
O2
Decent urgent
Gamow bag
Steroids
Ca2+ blockers?
Sildenafil
Effect of flying on the lungs:
Reduced ambient pressure which reduces PiO2 and thus PAO2 and thus PaO2
High A-aO2 may also contribute to patient hypoxia if they have significant lung disease
What is pressure at 150m?
pressure at surface (0m) is 1atm, then for every 10 m add 1
at 150m it’s 16atm
shallow water blackout
PaO2, PaN2, PaCO2 rise
Eventually CO2 builds up sufficiently to induce desire to breathe
Diver returns to surface
PaO2 falls, PaCO2 rises
What is decompression sickness?
N2 forced into tissue e.g. spinal cord, brain, organs etc. As diver rises volume of bubbles rises (pressure decreasing)
High Altitude Cerebral Oedema (HACE)