Lungs and Pleura Flashcards
1
Q
Alpha-1 antitrypsin deficiency is associated with?
A
EMPHYSEMA
Loss of AAT disrupts the protease-antiprotease balance in the lungs, allowing proteases, specifically neutrophil elastase, to act uninhibited and destroy lung matrix and alveolar structures.
2
Q
Most common type of emphysema
A
CENTRIACINAR - upper lobes (smokers)
3
Q
Most common pneumoconiosis in the world
A
SILICOSIS
Egg-shell calcifications in radiographic appearance
4
Q
Virchow’s Triad
A
- HYPERcoagulable state
- ENDOthelial injury
- STASIS of blood
HYPER ENDO STASIS
5
Q
Paraneoplastic syndrome where in Autoantibodies against neuronal calcium channels
A
Lambert Eaton Myasthenic Syndrome (LEMS)
