Breast

Question 1

Hallmark of epithelial hyperplasia

Answer 1

> 2 layers of cells in a duct (1 luminal and 1 myoepithelial)

Question 2

BREAST DUCT SYSTEMS:

Hormonally responsive, and where invasive breast carcinomas arise?

Answer 2

terminal duct-lobular unit

TDLU

Question 3

Type of cancer that outwardly may have the appearance of eczema, with skin changes involving the nipple of the breast

Answer 3

PAGET’s DISEASE

Question 4

Comprises the Nottingham score in evaluation of Breast Carcinoma

Answer 4

1. Tubule formation
2. Nuclear pleomorphism
3. Mitotic figures (/10 HPF)

Question 5

Trastuzumab as a hormonal treatment would most likely benefit:

Answer 5

HER-2 NEU (+) Breast Ca

vs

ER/PR (+) - Tamoixifen