Lungs and Breast Flashcards
diagnosis for pseudorosettes
metastatic adenocarcinoma
peripheral mass in the left upper lobe. what histochemistry?
p63
physical exam shows hirsutism and moon facies; lymphocytes with molding. what dx?
small cell carcinoma
mass circumscribing the right main bronchus, extending to the lumen. dx?
carcinoid tumor
long standing ulcerative colitis. round masses in both lungs. what immunohistochemistry?
TTF-1
history of alcoholism. thoracocentesis shows emphysema. what cells are predominant?
lymphocytes
most powerful stimulator of smooth muscle spasm
TNF-a
released from mast cells resulting in increased prermeability
bradykinin
coal miner; reveals black lung; the coal trapped is sequestered by what cells?
fibroblasts
coin lesion. dx?
hamartoma
sputum reveals acid fast bacilli. resembles what?
miliary TB
bronchoscopy discloses obstruction of the LEFT main bronchus. what tumor markes?
p63
most frequent form of extrapulmoo TB
scrofula
upper truncal obesity and depression; displays hilar mass; what cytologic features?
NE granules
barrel chest, hyperresonance on percussion and clubbing of digits. dx is emphysema. what histopathology?
destruction of the walls of airspaces without fibrosis
Q fever?
coxiella burnetti
what time frame?
4-5th day
least increased risk of lung CA
arsenic
filariform larval form, hyperinfection syndrome
strongyloides stercoralis
primary effusion lymphoma
HHV8
emphysema associated w scarring
irregular
mesothelioma patterns?
epithelial pattern
cystic fibrosis
pseudomonas aeruginosa
multinucleated giant cells
RSV
kidney shows membranoproliferative glomerulonephritis
good pastures syndrome
coating of what forms the ASBESTOS body
iron
leukemia on chemotherapy. open lung demonstrates viral pneumonia. what histopath expected on px?
confluent areas of caseous necrosis
Strep pneumo
scar formation
aspirin?
bronchospasm
aspergillosis features?
45 degrees regular branching points
breast shows lobular carcinoma in situ. decreased expression of what proteins?
E cadherin
BRCA1 promotes what cell function?
DNA repair
most likely cause of galactorrhea?
pituitary adenoma
dx for sarcomatous stroma in the breast?
medullary CA
jelly like tumor in the breast. dx?
colloid CA
+ for HEr2/nue but (-) for ER PR
invasive ductal CA
single file columns in the breast. what dx?
invasive ductal CA
biopsy shows malignant ductal epithelial cells. what therapy?
estrogen receptors
painful swelling of the breast. most commonly seen in the ff groups?
women of reproductive age
not a feature of BRCA1 mutation
ER positive reactivity
adaptive response of the breast?
metaplasia
least likely dx for bloody discharge?
phyllodes tumor
also known as Zuska
periductal mastitis
changes w non proliferative breast changes?
radial scar
not a feature of ILC
glandular formation
mammary CA, risk factors?
family history
mammographic calcification is common
DCIS
medullary CA
solid syncytium like sheets