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Pathology > Lungs and Breast > Flashcards

Lungs and Breast Flashcards

1
Q

diagnosis for pseudorosettes

A

metastatic adenocarcinoma

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2
Q

peripheral mass in the left upper lobe. what histochemistry?

A

p63

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3
Q

physical exam shows hirsutism and moon facies; lymphocytes with molding. what dx?

A

small cell carcinoma

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4
Q

mass circumscribing the right main bronchus, extending to the lumen. dx?

A

carcinoid tumor

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5
Q

long standing ulcerative colitis. round masses in both lungs. what immunohistochemistry?

A

TTF-1

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6
Q

history of alcoholism. thoracocentesis shows emphysema. what cells are predominant?

A

lymphocytes

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7
Q

most powerful stimulator of smooth muscle spasm

A

TNF-a

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8
Q

released from mast cells resulting in increased prermeability

A

bradykinin

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9
Q

coal miner; reveals black lung; the coal trapped is sequestered by what cells?

A

fibroblasts

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10
Q

coin lesion. dx?

A

hamartoma

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11
Q

sputum reveals acid fast bacilli. resembles what?

A

miliary TB

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12
Q

bronchoscopy discloses obstruction of the LEFT main bronchus. what tumor markes?

A

p63

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13
Q

most frequent form of extrapulmoo TB

A

scrofula

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14
Q

upper truncal obesity and depression; displays hilar mass; what cytologic features?

A

NE granules

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15
Q

barrel chest, hyperresonance on percussion and clubbing of digits. dx is emphysema. what histopathology?

A

destruction of the walls of airspaces without fibrosis

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16
Q

Q fever?

A

coxiella burnetti

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17
Q

what time frame?

A

4-5th day

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18
Q

least increased risk of lung CA

A

arsenic

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19
Q

filariform larval form, hyperinfection syndrome

A

strongyloides stercoralis

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20
Q

primary effusion lymphoma

A

HHV8

21
Q

emphysema associated w scarring

A

irregular

22
Q

mesothelioma patterns?

A

epithelial pattern

23
Q

cystic fibrosis

A

pseudomonas aeruginosa

24
Q

multinucleated giant cells

A

RSV

25
Q

kidney shows membranoproliferative glomerulonephritis

A

good pastures syndrome

26
Q

coating of what forms the ASBESTOS body

A

iron

27
Q

leukemia on chemotherapy. open lung demonstrates viral pneumonia. what histopath expected on px?

A

confluent areas of caseous necrosis

28
Q

Strep pneumo

A

scar formation

29
Q

aspirin?

A

bronchospasm

30
Q

aspergillosis features?

A

45 degrees regular branching points

31
Q

breast shows lobular carcinoma in situ. decreased expression of what proteins?

A

E cadherin

32
Q

BRCA1 promotes what cell function?

A

DNA repair

33
Q

most likely cause of galactorrhea?

A

pituitary adenoma

34
Q

dx for sarcomatous stroma in the breast?

A

medullary CA

35
Q

jelly like tumor in the breast. dx?

A

colloid CA

36
Q

+ for HEr2/nue but (-) for ER PR

A

invasive ductal CA

37
Q

single file columns in the breast. what dx?

A

invasive ductal CA

38
Q

biopsy shows malignant ductal epithelial cells. what therapy?

A

estrogen receptors

39
Q

painful swelling of the breast. most commonly seen in the ff groups?

A

women of reproductive age

40
Q

not a feature of BRCA1 mutation

A

ER positive reactivity

41
Q

adaptive response of the breast?

A

metaplasia

42
Q

least likely dx for bloody discharge?

A

phyllodes tumor

43
Q

also known as Zuska

A

periductal mastitis

44
Q

changes w non proliferative breast changes?

A

radial scar

45
Q

not a feature of ILC

A

glandular formation

46
Q

mammary CA, risk factors?

A

family history

47
Q

mammographic calcification is common

A

DCIS

48
Q

medullary CA

A

solid syncytium like sheets

Pathology (18 decks)

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