Lung Surfactants

Question 1

Actions

Answer 1

Replace the surfactant that is missing in the lungs of neonates with RDS

Question 2

Indications

Answer 2

Rescue treatment of infants who have developed RDS (missing surfactant)
Experimental: ARDS, infectious and inflammatory lung diseases

Question 3

Drug names

Answer 3

“-actant”
	Beractant
	Calfactant 
	Lucinactant 
	Poractant

Question 4

Pharmacokinetics

Answer 4

Begin to act immediately on instillation into the trachea

Question 5

Contraindications

Answer 5

Emergency drug; no contraindication

Question 6

Adverse effects

Answer 6

UNKNOWN

May or may not be related to the drug:

Patent ductus arteriosus
Hypotension
Intraventricular hemorrhage
Pneumothorax
Pulmonary air leak
Hyperbilirubinemia
Sepsis

Question 7

Assessment

Answer 7

History
	Emergency drug: no 
        contraindications
	Time of birth and 
         exact weight for 
         dosage

Physical exam for effectiveness of drug:

Temperature, respirations, lung sounds, endotracheal tube placement and patency, and chest movements
Blood pressure, pulse, and arterial pressure
Blood gases and oxygen saturation

Question 8

Diagnosis

Answer 8

Decreased cardiac output

Risk for injury

Ineffective airway clearance

Deficient knowledge

Question 9

Implementation

Answer 9

Monitor continuously

Suction before administration, but wait two hours after administration

Support for parents

Other supportive measures for premature infants