Lung structure and function Flashcards
Match the SA:Mass ratio of the lungs with the mammal it belongs to:
- Seals, Humans and Bats.
- 7cm2/g, 13 cm2/g, 100cm2/g.
Humans = 7cm2/g. Seals = 13 cm2/g. Bats = 100cm2/g.
What is the relative diameter of an alveoli?
They are very small, diameter roughly 100um (micrometers)
What is the SA:V ratio like for alveoli?
There is a huge SA:V for alveoli and the lungs in general.
What is the capillary bed surrounding the alveoli like?
It is very dense, nearly covers 87% of the alveoli.
What is the alveolar epithelium?
“A layer of cells separating the body tissues from the environment”.
What is the endothelium?
“A layer of cells separating the blood from the tissues.”
What is squamous epithelium?
“A thin and flat cell at an exchange surface.”
Alveoli contains an epithelial cell which is specialised to produce what?
Surfactant.
What does surfactant do and why is this beneficial?
It lowers the surface tension of water which allows us to inflate our lungs properly.
Why may premature babies have trouble inflating their lungs fully?
Their surfactant producing cells have not developed enough and therefore water has a high surface tension and the lungs cannot inflate properly.
What is Fick’s Law?
Rate of diffusion is proportional to the concentration gradient x surface area / diffusion distance.
According to Fick’s law, which factors can be increased to speed up the rate of diffusion?
Surface Area(:Volume ratio). Concentration Gradient.
According to Fick’s law, which factors can be decreased to speed up the rate of diffusion?
Diffusion distance.
According to Fick’s law, which factors can be increased to slow down the rate of diffusion?
Diffusion distance.
According to Fick’s law, which factors can be decreased to slow down the rate of diffusion?
Surface Area(:Volume ratio). Concentration Gradient.
How are the alveoli adapted to have a high surface area?
They are very small so their SA:V ratio is large.
How are the alveoli adapted to have a high concentration gradient?
Ventilation of alveoli maintains the gradient, as well as the circulation of blood.
How are the alveoli adapted to have a low diffusion distance?
Squamous epithelial cells.
The trachea, bronchi and bronchioles are known as dead space, what does this mean?
They are simply a passage for air and gas exchange does no occur here.
What is the function of the smooth muscle in the walls of the bronchi and bronchioles?
They allow the diameter of the airways to be altered to control movement of air into the alveoli.
What is the function of the C shaped rings of cartilage in the trachea and bronchi?
They prevent collapse of airway as pressure falls during inhalation they also allow expansion of oesophagus during swallowing.
Which airways contain most cartilage?
Trachea and Bronchi, to make sure the airway stays open.
How is cartilage found in the trachea and bronchi?
In a C-shaped formation.
What is the function of the goblet cells?
To produce mucus which collects dust and foreign particles such as bacteria.
What is the function of the ciliated epithelial cells?
They ‘waft’ the mucus up the throat to prevent it reaching the lungs.
What is the antagonistic pair in the wall of the bronchioles?
Smooth muscle and loose tissue with elastic fibres.
How does the antagonistic pair work in the bronchioles?
Smooth muscle contracts the airway and then elastic fibres recoil to open the airway back up.