Lung cancer

Question 1

What is a possible paraneoplastic feature of an adenocarcinoma?

Answer 1

Gynaecomastia

Question 2

List examples of paraneoplastic features associated with squamous cell lung cancer

Answer 2

Clubbing
Hyperthyroidism
HPOA-hypertrophic pulmonary osteoarthropathy
PTH-rp secretion, causing hypercalcaemia

Question 3

List examples of paraneoplastic features associated with small cell lung cancer

Answer 3

ADH
ACTH secretion
Eaton Lambert syndrome

Question 4

Secretion of ACTH or PTH is relevant to small cell lung cancer?

Answer 4

ACTH

Question 5

Secretion of ACTH or PTH is relevant to squamous cell lung cancer?

Answer 5

PTH

Question 6

Where are squamous cell carcinomas most likely to develop in the lungs and what can this cause?

Answer 6

Nearer the larger airways of the lung

- obstruction and lobar pneumonia

Question 7

Which lung cancers are near-endocrine in nature?

Answer 7

Small cell lung cancers

Question 8

What is the most common type of lung cancer in non-smokers?

Answer 8

Adenocarcinoma

Question 9

List contraindications to lung cancer surgery

Answer 9

SVC obstruction
FEV1 <1.5
Malignant pleural effusion
Vocal cord paralysis