Lung Cancer Flashcards
facts about Lung cancer
- leading cause of cancer-related deaths in the US
- 28% of all cancer deaths
- 58% mens
- African Americans have highest death rate
Lung cancer on Men
have a worse prognosis than women
Lung cancer on Women
- Develop lung cancer after fewer years of smoking.
- develop lung cancer at a younger age than men
- are more likely to develop small cell carcinoma than men
Most important Risk Factor of Lung Cancer
-Cigarette smoking=80-90% of all lung cancer
-inhaled carcinogens=exposure to 1 or more of the ff. or air pollution=significantly higher risk for lung cancer.
Asbestos
Radon
Nickel
Iron
Hydrocarbons
Arsenic
Air pollution
pathophysiology of Lung Cancer
- is not well understood
- arises from Bronchial epithelial cells(bronchogenic)
- cells grows slowly
- upper lobes of the lungs more common
- hypersecretion of mucus
Types of Primary Lung Cancer
- Non-small Cell Lung Cancer
- Squamos Cell carcinoma
- Large Cell (undifferentiated Carcinoma)
- Small cell Lung Cancer
Clinical Manifestation of Lung Cancer
-Asymptomatic=discovers during routine X-rays approximately 10% Manifestation depends: =type of primary lung cancer =Location of the Cancer =Metastatic Spread
- Persistent cough(productive and Hemoptysis)
Later Symptoms of Lung Cancer
Anorexia Fatigue Weight loss Nausea & vomiting Hoarseness Dysphagia Mediastinal involvement-> pericardial effusion, cardiac tamponade, dysrythmias
Diagnostics Studies of Lung Cancer
Chest X-rays- to identify mass or infiltrate
CT scan- single & most effective NON INVASIVE technique=>CT of the brain and bone scans complete evaluation for metastasis
MRI - instead of CT scan
PET scan(Positron Emission Tomography)
Sputum Cytology- identify malignant cell
*BIOPSY IS NECESSARY FOR DEFINITE DIAGNOSIS- Fine needle Aspiration and Video assisted Thorascopy (VAT)
Lung Cancer Staging
Stage 0—–Cancer in Situ
Stage 1—–Tumor limited to tissue origin
Stage 2—–Limited local spread
Stage 3—–Extensive local and regional spread
Stage 4—–Metastasis
prevention of Lung Cancer
- early screening for lung cancer
- smoking cessation
Treatment of Lung Cancer
SURGICAL THERAPY- 5 yr survival rate, stage2 40-60% 5yr survival rate
-Pneumonectomy(removal of entire lungs)
-Lobectomy(removal on 1 or more lobes)
-Lung Resection( segment or wedges removed)conserves lungs.
RADIATION THERAPY- done when pt. unable to withstand surgical resection due to co-morbidities
CHEMOTHERAPY- used in treatment on nonresectable tumors
-considered standard treatment
Etoposide(VePesid)
Carboplatin(Paraplatin)
Cisplatin(Platinol)
Paclitaxel(Taxol)
Complications: extremely toxic & debilitating
other Treatment/Therapy for Lung Cancer
Biologic and Targeted Therapy
- uses drug specifically targeting stages/areas of tumor growth
- fewer toxicities than with chemotherapy
Prophylactic Cranial Radiation: CAN get cells chemotherapy cannot( passes blood-brain barrios)
Bronchoscopic Laser Therapy: removes obstructive bronchial lesions.
Photodynamic Therapy: Exposes tumor to laser light for a period of time, destroying tumor cells.
Cryotherapy: tissue destroyed by freezing
Nursing management: Lung cancer POST OPERATIVE
- Post-operative Care
- Respiratory status
- Pain management
- Chest Tube Management
Nursing management: Lung cancer CHEMOTHERAPY
Kidney function