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Oncology > Lung Cancer > Flashcards

Lung Cancer Flashcards

1
Q

Epidemiology

Lung

A

Leading cause of cancer death.

Male/female ratio 1:1.

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2
Q

Etiology

Lung

A

Significant tobacco exposure. Smoking causes 87% LC.
Radon (2nd).
Occupational exp (tar, nickel, arsenic, chromium).
Pollution.

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3
Q

Carina vertebral level

A

T4-T5

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4
Q

Mediastinum components

A

Heart
Thymus
Great vessels

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5
Q

Clinical presentation
Local disease
Lung

A

Cough
Hemoptysis
Dyspnea
Chest pain

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6
Q

Clinical presentation
Regional disease
Lung

A

Dysphagia
SVCO
Hoarseness

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7
Q

Pancoast tumor

A

Pain in shoulder and arm
Atrophy of hand muscles
Horner’s syndrome
Bone erosion of ribs

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8
Q

Horner’s syndrome

A

Ipsilat miosis
Ptosis
Enophthalmos
Anhydrosis

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9
Q

Detection

Lung

A 
Chest x-ray
CTdirected PFNA 
Sputum cytology 
Bronchoscopy
Mediastinoscopy
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10
Q

Pathology

Lung

A

Adenocarcinoma (40%)
SCC (30%)
SCLC (20%)

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11
Q

Mets

Lung

A 
Liver
Brain
Bones 
Adrenal glands
Kidneys
Contralat lung
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12
Q

Chemo

Lung

A

Cisplatin and VP-16 for SCLC

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13
Q

PCI

Lung

A

SCLC

Adenocarcimoma

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14
Q

Doses

Lung

A

SCLC 45-54Gy

NSCLC 60-70Gy

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15
Q

OAR

Lung

A

SC 45Gy
Heart 45Gy
Normal lung 15Gy whole

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16
Q

Acute side effects

Lung

A 
Dermatitis 
Erythema
Esophagitis 
Dysphagia
Cough
Dry throat
Excessive mucus secretions
17
Q

Dysphagia occurs at what dose

A

30Gy

18
Q

Chronic SE

Lung

A

Dry unproductive cough
Fibrosis of lung and skin
Pneumonitis

19
Q

Pneumonitis symptoms

A

Dyspnea
Fevers
Night sweats
Cyanosis

20
Q

WBC level pt cannot be treated

A

2 000/mm^3 or less

21
Q

Platelet level pt cannot be treated

A

50 000/mm^3 or less

22
Q

Doxorubicin (Adriamycin) SE

A

Cardiac toxicity

23
Q

Lung ca not associated with smoking

A

Adenocarcinoma

Oncology (7 decks)

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