Breast Cancer Flashcards

1
Q

Epidemiology

Breast

A

Most common ca in women.
2nd cancer related death in women.
1 in 8 women will get BC.

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2
Q

Etiology

Breast

A
Gender (most significant)
Age 40-70(55)
Family history
Genes BRCA1,2
Hormone factors
Alcohol 
Radiation exposure
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3
Q

Prognostic factors

Breast

A
LN status most important (low risk fewer than 3; high risk 4+)
Tumor size 
Presence of mets
Histology
ER PR HER2 status
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4
Q

Breast between which ribs

A

2-6 rib

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5
Q

Name of ligament that supports the breast

A

Cooper’s

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6
Q

Number of IM nodes

Breast

A

8 total

4 per side

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7
Q

Region most common in breast

A

Upper outer quadrant of left breast

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8
Q

Mets

Breast

A
Bone
Lung
Brain
Liver
Eyes
Ovaries
Adrenal and pituitary gland
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9
Q

Clin. Pres.

Breast

A
Painless lump (most common)
Nipple discharge 
Nipple retraction, tenderness or pain
Skin changes
Alteration in breast contour
Lymphadenopathy
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10
Q

Annual Mammogram should start at what age

A

40

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11
Q

Synonym for lumpectomy

A

Excisional biopsy

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12
Q

Histology

Breast

A

Infiltrating ductal carcinoma

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13
Q

Radical mastectomy

A

Entire breast with overlying skin.
All axillary nodes
Pectoral muscles

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14
Q

Modified radical mastectomy

A

Breast
Some or all axillary nodes
Pectoralis minor (optional)

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15
Q

Lumpectomy

A

Tumor plus margin

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16
Q

Chemo drugs

Breast

A

Cyclophosphamide
Doxorubicin (Adriamycin)
Paclitaxel

17
Q

Hormone therapy

Breast

A

Tamoxifen

Aromitase inhibitors

18
Q

Doses

Breast

A

45-50Gy plus boost to total of 60-66Gy to tumor bed

19
Q

IM nodes tmt field

Breast

A

Tang field extended 3 cm beyond midline to Contralat side

20
Q

Erythema occurs

A

30Gy (3-4 wks)

21
Q

Dry desquamation occurs

A

40Gy

22
Q

Moist desquamation occurs

A

After 50 Gy

23
Q

Stage 1

A

Early disease: tumor confined to the breast (node negative)