Lung Flashcards
1
Q
2 Lung IHCs
A
TTF1+ (lung origin) Napsin A (lung adeno)
2
Q
Molecular Testing
A
EGFR Mut and ALK rearrangement (via FISH)
3
Q
Muts For Squamos Cell, Adenocarc, and SCLC
A
p53, K-Ras (smokers) and EGFR kinase (nonsmokers), and c-MET
4
Q
Adenocarcinoma (IHC, location, sex, smoking)
A
Intracytoplasmic production of mucin, peripheral, equally M and F, most frequent type in non smokers
5
Q
Squamos Cell (IHC, location, sex, smoking)
A
Keratin (although cytokeratin also in large cell) and intercellular bridges, central, males, closely correlated with smoking
6
Q
SCLC (location, smoking)
A
Central/close to hilum, strongly associated w/ smoking
7
Q
Azzopardi effect
A
SCLC strong invasion/spilling DNA into bvs
8
Q
Most Common Lung Tumor in Children
A
Carcinoid
9
Q
Carcinoid Appearance
A
Monotonous cells, very vascular
