LS, Discospondylitis, Rando Flashcards
Antibiotic recommended for bacterial encephalomyelitis?
metronidazole, enrofloxacin, chloramphenicol, TMS, 3rd gen cephalosporin
antibiotic recommended for discospondylitis?
1st gen cephalosporins (clavamox sound) - 17% Staph resistant
Cephalexin, cefazolin, TMS
what dog breeds most often diagnosed with disconspondylitis? prognosis?
Great Dane, Labs, Rott, GSD, Doberman, Eng Bulldogs
fair to good uncomplicated
what are complications of sx for LSS?
trauma, compression, implant failure, inadequate bony fusion, adjacent segment disease
infections (23% positive cultures of disc)
seroma
instability
neuro deterioration
what is the overall prognosis?
excellent to good 77% (some papers report higher)
73% (Dorsal lam + discectomy)
what is recurrence rate?
3-54.5% (one study 16.7% normal function, 54% if only had mild improvement)
compare presentations of BP avulsion injuries:
1) avulsion cranial (C5-C7)
2) avulsion caudal )C8-T2)
3) all (C6-T2)
1) musculocutaneous, axillary, subscapular, suprascapular
- loss of shoulder movement and elbow flexion
- few CS
2) radial, median, ulnar (radial nerve signs more common - 92% of cases)
- flexed limb but no weight bearing as can’t extend carpus/digits
- Horner’s and/or loss cutaneous trunci (C8-T1)
3) all nerves
- drag limbs knuckled over, shoulder more neutral
- sensory deficits common
what are signalment/common breeds that get steroid-responsive menigitis-arteritis?
young 6-18 months
74.2% are < 1year
Beagles, boxers, BMD, weimaraners, Nova scotia duck retrievers
presentation and CSF findings between the 2 forms (steroid-responsive menigitis-arteritis)?
acute form:
- hyperesthesia, cervical rigiditly, stiff gait, fever
- guarding neck
- polymorphonuclear nondegenerative, pleocytosis, increased TP, ~ RBC
chronic form:
- paresis, ataxia, menace deficit, anisocoria, vestibular signs
- primary mononuclear cells or mixed cells, normal or mildly increased TP
what BW can help to monitor therapy (steroid-responsive menigitis-arteritis)?
acute form:
-c-reactive protein
chronic form:
- macroglobulin
what are the components and locations of ventriculoperitoneal shunt?
ventricular catheter
control valve
abdominal or distal catheter
ventriculoperitoneal shunt - complications of placement?
shunt infection, shunt malfunction/blockage, under shunting, catheter migration, control valve function, seizures
what are the systems described to evaluate brain sx post-op?
response criteria in solid neoplasms (RECIST)
response assessment in neuro-oncology (RANO)
MacDonal criteria
what is diagnostic yield for stereotactic biopsy? morbidity rates?
> 90% especially for cancer
morbidity rates up to 27% reported (but newer rates ~5%)
what are high risk breeds of LSS?
GSD, Dobie, Rottie, BMD, Dalmation, Boxer, Irish Setter, lab
what is intermittent claudication?
paroxysmal manifestations - caudal lumbar pain or PL cramping, pain, weakness from vascular compromise or compression of nerve roots of cauda equina
what C.S/presenting complaint in dog with LSS have worse prognosis?
urinary and/or fecal incontinence
what congenital cranium abnormalities may benefit from sx?
intracranial arachnoid diverticula
dermoid/epidemoid cysts
congenital hydrocephalus
disorders associated with malformation of caudal cranial fossa and craniocervical junction
Signalment for calcinosis circumscripta?
< 1yr, large breed. (GSD overrepresented)
prognosis with surgery for calcinosis circumscripta?
no recurrence upto 24 mo post dorsal laminectomy
what causes osteochondroma?
arise secondary to migration of chondrocytes from physeal region into metaphyseal region of bone
continued cartilage formation
prognosis for osteochondroma?
if a accessible to excise - favorable
what are the 3 stages of distemper infection?
gray matter disease:
- ~1 week post infection - nonsuppurative ME
- often die within 2-3 weeks (often with seizures)
- may recover or progressive to next
white matter disease:
- ~3 weeks post infection
- most common form (likely due to subclinical GM stages)
- may recover with minimal CNS injury or infection
necrotizing meningoencephalitis
- ~4-5 weeks post infection
- nonsuppurative inflammation
- uveitis, chonoretinitis
some deteriorate and die; others slowly recover
distemper infection - diagnostics? treatment?
RT - PCR (whole blood, urine, CSF)
IHC antigen biopsy - nasal mucosa, foot pad epithelium, haired skin
supportive treatment
prognosis guarded
list surgical techniques for treating brachial plexus avulsions
neurotization (re-enervation of denervated motor or sensory end organ (sacrifice donor nerve))
reimplantation - through hemilaminectomy
end to end suturing/anastomosis (without graft)
what is the prognosis for avulsion injuries to the brachial plexus?
grave if radial nerve avulsion
give case 4-6 weeks until grave prognosis is given
what is a myelodysplasia dysraphism?
congenital malformation - incomplete and abnormal fusion of neural tube win sagittal plane - bunny hopping
what breed is predisposed to a myelodysplasia dysraphism ?
weimaraner
what is the treatment for a myelodysplasia dysraphism?
no treatment
not in pain and doesnt progress
what are methods of cranial reconstruction, protection of meninges?
Meninges:
direct suturing
fascia temporalis
porcine SIS
Cranium:
Replacement of excised skull bone or calvarial allografts
acrylic cranioplasty
metallic mesh
what is most informative/sensitive test for evaluating cauda equine syndrome?
somatosensory evoked potenitals
list four variant radiographic studies that can be used to evaluate LSS
advantages/disadvantages of each?
venography - can have tech errors
myelography - limited due to location of enddural sac (cant evaluate LS IVD vs LS IV foramen)
epidurography - easier/superior to myelographs and less side effects
discography - inject into NP; could lead to IVD degeneration
for LS fracture/subluxation - affected dogs can have up to ____% displacement of canal without major neuro deficits
100%
list reported techniques to repair LS fractures
- transilial pinning
- modified segmental spinal instrumentation
- combined Kirschner-ehmer/dorsal spinal plate fixation
- pins/screws and PMMA
- locking plate (SOP)
where to focus pins on LS fracture?
cranial - implants intact pedicles and body L7
caudal - implant sacrum, tuber sacrale, body of ilium
what are the 2 approaches to pituitary?
transcrally (transphenioidally)
ventral paramedian
list complications to (short vs long) of cranial sx?
short term:
- aspiration pneumonia
- seizures
- recurrence intracranial bleeding
- increased ICF
long term:
- infection
- pneumocephalus
- compression brain secondary to fibrous tissue or overlying musculature
what is the difference in pathophysiology for non communication, communicating, and compensatory for secondary hydrocephalus?
non communicating: obstruction of flow from ventricles to SAS
communicating: decreased resorption by arachnoid villi or increased production of CSF
compensatory: loss of brain parenchyma
list three approaches to foraminotomy: advantages vs disadvantages
dorsal laminectomy:
- to see IV foramen.
- can’t see L7 nerve root exit well
lateral approach:
- with foraminotomy created from lateral side and direct to vertebral canal.
- dont directly observe cauda equina. - tough to see entry zone of foramen
osteotomy of wing of ilium:
- not used yet
lateral approach:
- access IVD and foramen and dont affect ZPJ
how can you improve visibility for foraminotomy for dorsal laminectomy?
remove medial part of caudal articular process L7
durotomy decreases ICP by ___% versus 15% by craniotomy alone?
65%
which vertebral neoplasms are chemo responsive or at least reported to be?
lymphoma, plasma cell tumor, OSA, multiple myeloma
list extradural noeplasma of vertebra?
osa, lymphoma, histiocytic sarcoma complex, infiltrative lipoma, myxoma, calcinosis circumscripta, osteochondroma, chondrosarcoma
list intradural/extramedullary neoplasms of vertebra?
meningioma, nerve sheath tumor, extrarenal (ependymoma, neuropeithelioma)
list intramedullary tumors of vertebra?
ependyma, glia for primary origin, metastatic for secondary, astrocytoma
what breeds are overrepresented with histiocytic sarcoma complex?
Bernese mt dogs, golden, rott, flat-coated retriever
MST for histiocytic sarcoma complex?
3-4 months
recurrence rate of infiltrative lipoma
36-50%
what is a myxoma? breeds that are overrepresented?
rare tumor of synovium
dobies and labs.
ventrolateral stabismus from what nerve injury?
oculomotor