LP 4 Flashcards

1
Q

surse de acid uric

A

-baze azotate purinice

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2
Q

loc formare acid uric

A

ficat

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3
Q

soarta acid uric

A

reab 98-100 tub contort prox
0-2 secretie tub contort distal

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4
Q

condtii pentru formare de cristale

A

ph fiziologic, con peste 6.4mg/dl

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5
Q

clasif metode de dozare

A
  1. oxidare cu fosfotungstat sau uricaza
    2.oxidare enzimatica
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6
Q

aplicatia practica-dozare prin metoda enzimatica

A

acid uric in prez de uricaza form allantoina si apa oxigenata
apa oxigenata reduce o dianisidina

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7
Q

val de referinta

A

femei 2,5-6mg/100
barbat 2.5-7mg/100

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8
Q

factorii care produc hiperuricemie

A

-formare crescuta de purine(aport alimentar crescut de purine, catabolism mare purine, formare mare de purine=guta, sindr lesh-nylan)
-eliminare scazuta de acid uric(inf renala, intoxicatii cu plumb)

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9
Q
A
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