LP #105 The Circulatory System Flashcards

1
Q
  • complex network of vessels
  • basic fxn: deliver oxygen & nutrients to the cells, & remove tissue wastes
  • primary role n maintaining homeostasis
A

Circulatory system

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2
Q

2 components to circulatory system

A
  • cardiovascular-2-way system:
  • delivers blood to tissues
  • removes it from tissues returns it to heart
  • lymphatic- one-way:
  • removes excess fluid from tissues & returns it general circulation
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3
Q

Vascular system is a network consisting of 3 types of blood vessels:

A
  1. arteries: carry blood away from heart
  2. Blood capillaries: site of exchange of o2/ nutrients & sates
    * extensive network
  3. Veins: return blood to heart
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4
Q

Carry fluid that leaks out of blood vessels into interstitial spaces & transports it back to heart=

A

Lymphatic vessels

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5
Q

3 lymphatic vessels=

A
  1. lymph capillaries
  2. lymphatic collecting vessels
  3. lymphatic trunks
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6
Q

Tunica: layer

  • inner layer?
  • middle layer?
  • outer layer?
A
  1. Tunica intima
  2. Tunica media
  3. Tunica adventitia
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7
Q
  • aka tunica interna
  • inner most layer
  • composition: simple squamous cells; form a smooth endothelial surface- reduces friction to blood flow
  • in direct contact with blood
A

Tunica intima

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8
Q
  • middle & largest layer
  • composition: mostly smooth muscle fibers arranged in circular layers
  • responds to sympathetic Innervation
  • changes to diameter of bv lumen (vasodilation/ vasoconstriction)
A

Tunica media

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9
Q
  • aka tunica adventitia
  • outermost layer, relatively thin
  • composition: loosely arranged collagen fibres
  • protect & anchor vessel to surrounding structures
  • forms mesh network containing nerve fibres, small blood vessels & lymphatic vessels that serve the artery itself
A

Tunica externa

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10
Q
  • carry blood away from heart
  • diverge from large to small vessels
  • systemic arterial blood is oxygenated
  • arteries begin in heart and end, via arterioles, in capillary beds
  • relative size of layers varies between types of aa
A

Arteries

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11
Q

Types of arteries

A
  1. elastic (conducting)
  2. muscular (distributing)
  3. arterioles
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12
Q
  • large diameter blood vessels
  • carry blood from heart
  • contain mostly elastin in tunica media
A

Elastic (conducting)

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13
Q
  • smaller diameter blood vessels

- contain more smooth mm than elastin

A

Muscular (distributing)

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14
Q
  • smallest diameter blood vessels

- contain mostly smooth mm

A

Arterioles

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15
Q
  • carry blood towards heart
  • converge from small to larger vessels
  • systemic venous blood is deoxygenated
  • veins begin in capillary beds (as venules) & end in heart
A

Veins

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16
Q

Types of veins

A
  1. Venules

2. Veins

17
Q
  • small vessels
  • transport blood from tissues to larger veins
  • endothelium covered by fibroblastic cells
  • thin tunic intima & tunica externa
  • porous
18
Q
  • small, thin vessels in tissues
  • tunica externa is thickest layer
  • tunica media relatively thin
  • large lumen
  • contain valves
19
Q

Structures of veins determine fxns:

  • large lumen:?
  • little muscle:?
  • valves:?
A
  1. Blood reservoir
  2. Need help returning blood to heart (mostly against gravity)
  3. (Extensions of Tuncia intima) prevent back flow of blood
20
Q

Mechanisms that assist venous return

A
  • skeletal mm contractions
  • breathing
  • valves
21
Q
  • smallest blood vessels
  • walls are 1 cell thick: Tuncia intima only
  • fxn: site of gas/fluid exchange betweeen arterial & venous sides of circulatory system
A

Capillaries

22
Q

Types of capillaries

A
  1. Continuous
  2. Fenestrated
  3. Sinusoidal
23
Q
  • cells joined by tight junctions
  • intercellular clefts: breaks b/w cells
  • limited passage of fluids & volutes
  • found in:
  • skin
  • mms
  • brain
A

Continuous

24
Q
  • large pores covered by network of proteins (basal lamina)
  • allow larger organic molecules & greater volume o fluid to flow into interstitial space
  • found where absorption/ secretion is required, ex.
  • intestine
  • endocrine glands
A

Fenestrated

25
- leaky: large intercellular clefts - passage of proteins & blood cells into interstitial space - found where passage of large particles is necessary, ex. * liver * bone marrow * lymphoid tissue
26
-capillary bed=
Large capillary network
27
2 components of capillary bed
- vascular shunts | - true capillaries
28
- short vessels b/w arterioles & venule - main thoroughfare from one side of capillary bed to other - also known as a metarteriole
Vascular shunt
29
- side-spread network of blood vessels | - reach all tissue areas
True capillaries
30
- leads into metarteriole - joints to postcapillary venule that drains capillary beds - feeds capillary bed
Terminal arteriole
31
- found between metarterioles & capillaries - smooth mm rings that constrict lumen to restrict blood flow to capillaries - minimize BF to areas requiring less blood at a given time
Pre-capillary sphincters
32
- many tissues receive blood from more than one vessel * anatomical & physiological redundancy - margining of 2 or mor blood vessels to a region is called an anastomosis - both arteries & veins anastomose * veins more than arteries
Vascular anastomoses
33
- cyclical from heart to lungs & back to heart - in pulmonary circuit: * arteries carry deoxygenated blood away from heart (to lungs) * veins carry freshly oxygenated blood to heart (from lungs)
Pulmonary system
34
- returns leaked fluid (lymph) to general circulation - important in maintaining fluid balance - 3-4L of lymph produced daily (2/3 blood vol) - lymphatic system is one-way system (unlike cardiovascular system) - as lymph travels toward venous system (ultimately into subclavian veins), it is cleansed by WBC-rich lymph nodes
Lymphatic system
35
lymphatic system: | Adaptations?
- minivalves | - anchors
36
Lymph flows into progressively larger vessels:
``` Lymph capillaries To Collecting vessels To Trunks To Ducts ```
37
Lymphatic system: - larger vessels have same 3 tunics as veins, but much thinner - lymphatic valves have many more valves than veins - mechanisms hat assist lymph return: ?
- skeletal mm contractions - breathing - valves - movement of surrounding tissue *both components of the circulatory system are important o maintaining fluid balance in the body.