Lower GI

Question 1

What is the myenteric plexus?

Answer 1

The second brain which decides when the GI contracts.

Question 2

What cells are present in the myenteric plexus?

Answer 2

Ganglion cells

Question 3

What is the disease called when you don’t have ganglion cells?

Answer 3

Hirschprung disease

Answer 4

Biopsy - Hypertrophies nerve fibres

Question 5

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Question 6

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Question 7

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Question 8

Acute colitis - cause

Answer 8

pseudomembranous colitis due to antibiotics wiping out other gut bactiera but not C diff infection

these antibiotics are:

cipro, cephalosproins, clindamycin

Question 9

Diagnosis of acute colitis

Answer 9

Exotoxin stool assay

Question 10

Treatment of acute colitis

Answer 10

Side room
Vanco/metronidazole

Question 11

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Question 12

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Question 13

Ischemic colitis

Question 14

Crohns vs UC

Question 15

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Question 16

What are polpys and what increases your risk?

Answer 16

Benign dysplastic growth

Question 17

Colorectal cancer - risk factors

Answer 17

Low fibre, high fat diet, no exercise, obesity, chronic IBD

Question 18

Inherited conditions increasing risk of colorectal cancer

Answer 18

Familial adenomatous polyposis
Gardner’s syndrome
Hereditary non polyposis colorectal cancer/Lynch syndrome

Question 19

LEARN TEH DUKE and TNM staging

Question 20

Gardner’s syndrome

Answer 20

Subtype of FAB with extra-intestinal manifestations

Question 21

in which of crohns vs uc do you get granulomas?

Answer 21

CROHNS - non caseating

Question 22

Bloody diarrhoea - uc or crohns

Answer 22

UC

Question 23

Diagnosit test for cdiff infection?

Answer 23

stool sample

Question 24

Which gene is mutated in FAP?

Answer 24

APC gene - adenomatous polyposis coli