Cardio/cancer? Flashcards

1
Q

What does neutrophil mean?

A

Acute inflammation
Macrophages - late acute inflammation
Lymphocytes and plasma cells - chronic inflammation

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2
Q

Signet ring cells - pathology

A

Krukenberg tumour

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3
Q

Symptoms of krukenberg tumour

A

Abdo distension
Fluid thrill
Abdo pain

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4
Q

Serous cyst adenoma

A

Common general cyst, not cacnerous

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5
Q

Teratoma - prognosis

A

Good

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6
Q

Another name for germ cell cancer

A

Mature teratoma

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7
Q

HPV strain for cervical cancer

A

high risk - 16 and 18

low risk - 11 and 6

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8
Q

PID cause UK

A

Ascending infection, caused in the UK - chlamydia and gonorrhoea

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9
Q

PID cause in the world

A

TB
Schistosomiasis

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10
Q

PID symptoms

A

itPeritonitis
Intestinal obstructions due to adhesions
Bacteremia
Infertility
Fitz Hugh Curtis Syndrome - adhesion between peritoneal wall and liver

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11
Q

Fitz Hugh Curtis Syndrome symptoms

A

Deranged LFTS
RUQ pain
Pelvic pain

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12
Q

HPV virus what does it produce and bind to to cause cancer

A

e6 - p53
e7 - binds to retinoblastoma

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13
Q

CIN what does it stand for

A
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14
Q
A

Grade 3 - entire epithelium

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15
Q

ewti

A
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16
Q

CIN occurs in which part of the cervix?

CIN vs CGIN

A

Squamous epithelium - squamous cell carcnoma (80 percent)

Cervical glandular intraepithelial neoplasia - these form adenocarcinomas (20 percent)

17
Q

What are the two vaccines for HPV?

A

Gardasil (4 types)
Ceravix (only protects against high risk aka 16 and 18)

18
Q

Endometrial cancer types and epidemiology

A

Type 1 - oestrogen dependent, in younger patients, atypical endometrial hyperplasia

Type 2 - less oestrogen dependent, in older patients, atrophic endometerium

pten, kras etc with endometrial cancer

19
Q

Staging for Endometrial cancer

A

FIGO staging - learn it

20
Q

Gestational trophoblastic disease

A

Hydratiform moles

Choriocarcinoma
???

21
Q

Complete/partial mole symptoms

A

very high HCG
HCG is very similar to TSH, hence you get TSH-like symptoms
Spontaneous abortion
2.5 percent = cancerous

22
Q

Complete mole vs partial mole

A

Complete mole - sperm fertilisation of empty egg = snowy storm appearnce

Partial mole - 2 sperm + 1 egg - dispermy

23
Q

Choriocarcinoma

A

Post abortion????

24
Q

Theories for endometriosis

A

Retrograde menstruation - blood goes backwards from period, but this doesn’t explain why you’d get peritoneal deposits

Metaplasia of peritoneu

Chocolate cyst + powder burns seen macroscopically

25
Q

Signet ring cell - where is it found?

A

A type of cell in the stomach

26
Q

What is a krukenberg tumour?

A

Mets from a GI tumour resulting in mucin-secreting tumour

27
Q

What is the cause of nutmeg liver

A

Right sided heart failure

28
Q

Rose spots

A

Paratyphoid fever, conspitation et

29
Q

Prinzmetal angina

A

coronary artery spam due to cocaine

30
Q

Dressler syndrome

A

Pericarditis 4 weeks after MI

31
Q
A

Ventricular aneurysm - no pain

Pain but widespread ST elevation - pericarditis

32
Q
A

too thin, too thick, too stiff

dilated, hypertrophic, ??? cardiomyopathic

33
Q
A

chronic diarrhoea, fatigue and abdo pain