LORAZEPAM Flashcards
0
Q
MOA
A
+MODULATOR FOR GABAA RECEPTORS BINDS TO BENZO RECEPTOR SITE ON CHLORIDE CHANNELS AND POTENTIATES BINDING AND EFFECTS OF GABA INCREASES INTRACELLULAR CL CONCENTRATION LEADING TO HPERPOLARIZATION OF THE CELL
1
Q
DRUG CLASSIFATION
A
ANTICONVULSANT / SEDATIVE/ HPNOTIC/ BENZO
2
Q
PHARM
A
ONSET- 1-5 M IV 15-30 IM
PEAK EFFECTS- 15-20 M IV, 2 HOURS IM
DRURATION 6-8 H
HALF LIFE 10-20 H
3
Q
INDICATIONS FIELD USE
A
MAJOR MOTOR SEIZURES
PRE MEDICATIONS FOR CARDOVERSION
ACUTE ANXIETY
4
Q
CONTRAINDICATIONS
A
HYPERSENSITIVITY
5
Q
SIDE EFFECTS
A
HYPOTENSION, DROWSINESS, HA, AMNESIA, REPIRATORY DEPRESSION, BLURRED VISION, N+V
6
Q
DOSE
A
ADULT 0.5-2MG (0.1MG/KG) IV, IO
ADULT 1-4MG IM
PEDI 0.05MG/KG IV,IO
7
Q
PRECAUTIONS
A
HAVE BENZO ANTAGONIST AVAILABLE
8
Q
DRUG TO DRUG
A
ADDITVE EFFECTS WITH CNS DEPRESSANTS AND ETOH
