HALOPERIDOL Flashcards
MECHANISM OF ACTION
MESOLINBIC D1/D2 ANTAGONIST DEPRESSES RELEASE OF HYPOTHALAMIC AND HYOPHYSEAL HORMONES; DEPRESSES THE RETICULAR ACTIVATING SYSTEM, AFFECTING BASAL METABOLISM, BODY TEMP WAKEFULNESS VASOMOTOR TOME AND EMESIS.
DRUG CLASSIFICATION
BUTYROPHENONE ANTIPSYCHOTIC/NEUROLEPTIC
PHARMACOKINTETICS
ONSET 30-45 M
PEAK EFFECTS 10-20M
DUTATION-VARIES
HALF LIFE 3-35 H
INDICATIONS FIELD USE
acute psychotic episode
contraindications
cns DEPRESSION
AGITATIN SECONDARY T SHOCK OR HYPOXIA
SIDE EFFECTS/ ADVERSE REACTIONS
EPS, INSOMNIA RESTLESSNESS, DROWSINESS, SEIZURES, DRY MOUTH, CONSTIPATION, RESPIRATORY DEPRESSION, TACHCARDIA, HYPOTENSION, PROLONGED QT SYNDROME, TORSADES
DOSE
ADULT 5 MG Q 4-8H PRN
KIDS 1-3MG IM Q4-8H PRN MAX 0.15MG/KG/DAY
PRECAUTIONS
MAYIMPAR PHYSICAL AND MENTAL ABILITIES MAY CAUSE ORTHOSTATIC HYPOTENSION MAY CAUSE EPS-DYSTONIC REACTION.
DRUG-DRUG
CAUTION IN PATIENTS TAKING LITHIUM, MAY CAUSE ENCEPHALOPATHIC SYNDROME (BRAIN DAMAGE)
MAY INCREASE CHANCE OF HYPOTENSION WHEN TAKEN WITH ANTIHYPERTENSIVES ADDITIVE EFFECTS WITH DEPRESSANTS AND OTHER ANTI PSYCHOTICS INCREASED CNS DEPRESSION