Long QT and Brugada

Question 1

What channels are affected in Brugada syndrome?

Answer 1

Cardiac sodium channel

Question 2

What is the gene affected in Brugada syndrome?

Answer 2

SCN5A

Question 3

What are the ECG changes in Brugada syndrome?

Answer 3

ST elevation in leads V1-V3 with a RBBB appearance

Question 4

Describe Jervell and Lange-Neilsen syndrome.

Answer 4

Congenital bilateral sensorineural deafness
Long QT
Autosomal recessive

Question 5

Describe Romano-Ward syndrome.

Answer 5

Isolated long QT (nothing else affected)
Autosomal dominant
Most common form of congenital long QT syndrome

Question 6

In what gender is Brugada syndrome most common?

Answer 6

Males (8:1)

Question 7

How do you find out the risk of sudden cardiac death with hypertrophic cardiomyopathy?

Answer 7

Use the HCM risk calculator (dunno where tho)

Question 8

At what percentage risk of sudden cardiac death would you implant a defib?

Answer 8

4%

Question 9

What is the epsilon wave and what condition is it associated with?

Answer 9

Late spike in the QRS complex

Arrhythmogenic right ventricular cardiomyopathy