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CNS > Location DDX > Flashcards

Location DDX Flashcards

1
Q

Posterior Fossa- Pediatric

A 
Pilocytic Astrocytoma
Medulloblastoma (vermis)
Ependymoma
Choroid Plexus Papilloma
AT/RT (infant)
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2
Q

Supratentorial/Cerebral- Pediatric

A 
Ganglioglioma
DNET
PXA
CNS Embryonal Neoplasm
Ependymoma
AT/RT
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3
Q

Brainstem- Pediatric

A

Pilocytic Astrocytoma

Diffuse Midline Glioma- H3 K27M

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4
Q

Spinal Cord Intramedullary- Pediatric

A 
Ependymoma
Pilocytic Astroctyoma
Diffuse Midline Glioma- H3 K27M
Drop metastasis
Myxopapillary Ependymoma
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5
Q

Spinal Cord Intradural/Extramedullary- Pediatric

A

Clear Cell Meningioma
Schwannoma
Drop metastasis
Melanocytoma/Melanoma

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6
Q

Spinal Cord Extradural- Pediatric

A

Bone tumor (EWS)
Meningioma
Abscess
Vascular Malformation

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7
Q

Extra-axial/Dural/Leptomeningeal- Pediatric

A

Secondary Lymphoma/Leukemia
Meningeal Rhabdomyosarcoma
EWS
Diffuse leptomeningeal glioneuronal tumor
Meningeal Gliomatosis
CSF dissemination of Medulloblastoma or CNS embryonal tumor

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8
Q

Intrasellar

A 
Pituitary Adenoma
Craniopharyngioma
Rathke Cleft Cyst
Pituictyoma
Spindle Cell Oncocytoma
Granular Cell Tumor
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9
Q

Supracellar/Hypothalamic/Optic Pathway/ Third Ventricle- Pediatric

A 
Germinoma/Mixed Germ Cell Tumor
Craniopharyngioma
Pilocytic Astrocytoma
Pilomyxoid Astrocytoma (infant)
Langerhans Cell Histiocytosis
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10
Q

Pineal- Pediatric

A 
Germinoma/MGCT
Pineocytoma
PPTID
Pineoblastoma
Pineal Cyst
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11
Q

Thalamus- Pediatric

A

Pilocytic Astrocytoma

Diffuse Mid-line Glioma, H3 K27M-mutant

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12
Q

Cerebellopontine Angle- Pediatric

A

Vestibular Schwannoma (NF2, internal auditory meatus)
Choroid Plexus Tumor
AT/RT

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13
Q

Lateral Ventricle - Pediatric

A

Central Neurocytoma
SEGA (tuberous sclerosis)
Choroid Plexus Papilloma
Choroid Plexus Carcinoma (infant)

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14
Q

Nerve Root/Paraspinal- Pediatric

A

Neurofibroma (NF1)
MPNST
Melanotic Schwannoma/Malignant Melanotic Schwannian Tumor (Carney Complex)

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15
Q

Supratentorial/Cerebral- Adult

A

Diffuse Glioma
GBM
Metastases (grey-white junctions)
Lymphoma (periventricular)

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16
Q

Posterior Fossa- Adult

A

Metastasis
Hemangioblastoma (cyst w/ mural enhancing nodule)
Choroid Plexus Papilloma

17
Q

Brainstem- Adult

A

Diffuse Glioma/ Gliomatosis Cerebri

Met

18
Q

Spinal Cord Intramedullary- Adult

A

Ependymoma
Diffuse Midline Glioma, H3 K27M-mutant
Myxopapillary Endymoma (Filum Terminale)
Paraganglioma (Filum Terminale)

19
Q

Spinal Cord Intradural/Extramedullary- Adult

A

Schwannoma (dumbell shape)
Meningioma
Melanocytoma/melanoma
MPNST (NF1)

20
Q

Spinal Cord Extradural- Adult

A 
Herniated Disc
Postoperative Scar
Secondary Lymphoma
Met
Abscess
21
Q

Extra-axial/Dural/Leptomeningeal- Adult

A 
Meningioma (dural tail)
SFT/Hemangiopericytoma (dural tail)
Met
Secondary Lymphoma/Leukemia
Marginal Zone Lymphoma
Rosai-Dorfman Disease
IgG4 Dx and Collagen Vascular Disorders
Meningeal Carcinomatosis/Melanomatosis/sarcomatosis/ lymphomatosis/ hemangoblastomatosis
22
Q

Supracellar/Hypothalamic/Optic Pathway/ Third Ventricle- Adult

A

Colloid Cyst
Craniopharyngioma
Chordoid Glioma (ant 3rd ventricle)

23
Q

Pineal- Adult

A

Pineocytoma
PPTID
Pineal Cyst

24
Q

Thalamus- Adult

A

DMG, H3 K27M mutant
GBM
Lymphoma (multifocal)

25
Q

Cerebellopontine Angle- Adult

A 
Vestibular Schwannoma (internal auditory meatus)
Meningioma
26
Q

Lateral Ventricle - Adult

A 
Central Neurocytoma
SEGA (tuberous sclerosis)
Choroid Plexus Papilloma
Subepnedymoma (+/-E)
Meningioma
27
Q

Nerve Root/Paraspinal- Adult

A 
Schwannoma (dumbbell shape)
Meningioma
Secondary Lymphoma
Neurofibroma (NF1)
MPNST
Melanotic Schwannoma/Malignant Melanotic Schwannian tumor (carney complex)
28
Q

Craniopharyngioma

A

Most frequent supratentorial tumor in children. Usually suprasellar, with 50% having an intrasellar component, occasionally entirely intrasellar. Imaging shows cystic structure with calcification.

29
Q

Germinoma

A

Most commonly occurs in the pineal area, while uncommon the 2nd most common site is the suprasellar region.

CNS (17 decks)

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