Localisation In Clinical Neurology Flashcards
What do we mean by localisation
Where the lesion is responsible for patients that the symptoms and signs are based on
Why is localisation important
We cant image every patient so we need to have an ideo of where the lesion is localised to decide on what imaging to carry out
What are the 4 types of localisation
Focal
Multi focal
Diffuse
Specific
What is a focal localisation
Single locus that accounts for patients symptoms and signs
What is multi focal localisation
Involves more than one locus but loci remain discrete i.e you cant localise the lesion to one part of the brain
What is diffuse localisation
Widespread dysfunction of a part of the nervous system
What is specific pattern- give an example
Parkinsons disease
What are the lobes of the brain
- Frontal
- Parietal
- Temporal
- Occipital
What is the role of the frontal lobe
Motor function (pre-central gyrus)- motor function of the opposite side of the body
Brocas area which controls the speech output
Emotions
What is the role of the parietal lobe
Post-central gyrus- sensation of the opposite side of the body
What is the role of the temporal lobe
Memory
Dominant hemisphere contains the wernickes area which controsl the comprehension of speech
What is the role of the occipital lobe
Control the vision
What are the 3 segments of the spinal cord
Cervical
Thoracic
Lumbar
At what segment does the spinal cord end in
L1
After l1 what is the structure that comes at the end of the spinal cord
Cauda equina
In the spinal cord what roots are there
Dorsal root
Ventral root
What is the role of the dorsal root
Allow motor neurones to enter the spinal cord (sensory)
What is the role of the ventral root
Allow motor neurones to exit the spinal cord (motor)
What is the central nervous system made of
Brain
Spinal cord
Meninges
What is the peripheral nervous system made of
Nerve roots
Nerves including the cauda equina
Neuromusclar junction
Muscle
What are the signs in a UMN
Increased tone (spasticity) Weakness with no wasting Hyperreflexia Upgoing plantars Hypertonia Clonus
What is UMN a sign of
Lesion in the CNS
What are the LMN signs
Hyporeflexia Hypotonia Muscle wasting (atrophy) Fasciculations Normal plantars
Where is the lesion in LMN
PNS
What are the 3 important spinal tracts
Spinothalamic tract
Corticospinal tract
Dorsal columns
What are the sensory tracts
Spinothalamic tract
Dorsal columns
What are the motor tracts
Corticospinal tract
What sensation does the spinothalamic tract detect
Pain
Temperature
Coarse touch
What sensartion does the dorsal column detect
Fine touch
Vibration
Position
Where does the spinothalamic tract start
In the peripheral nerve into the dorsal root and crosses at the level of the spinal cord entry and crosses close to the central canal
Where does the dorsal column start
In the peripheral nerve through the dorsal nerve root and goes up to the medulla to cross
Where does the corticospinal tract start and descend to
Starts in the motor cortex and descends and crosses at the medulla and ends up in the anterior cell
What reflex does the biceps test for
C5/6
What reflex does the brachoradialis (supinator) reflex test for
C6
What reflex does the triceps reflex test for
C7
What refelx does the knee reflex test for
L4
What reflex does the ankle reflex test for
S1
What investigations can be carried out for a neuro disease
CT, CTA, CTV- has radiation
MRI, MRA,MRV- no radiation
Angiography
What does an EEG look at
Routine, sleep eeg and epilepsy
What is NCS used for
This is stimulation of different peripheral nerves that measures both sensory and motor function. It assess peripheral neuropathy and diagnosing entrapment
What is an EMG and what is it used to assess
This is a fine needle inserted into the muscle to look for spontanoue activity and motor unit potential you assess for peripheral neuropathy and neuromuscular disorders
When is a lumbar puncture contraindicated
In patients with symptoms and signs of increased ICP
What are the indications for lumbar puncture
Meningits
MS
Encephalitis
What does a CSF look at
Glucose Protein Cells Blood breakdown products Oligolocal bands for diagnosis of MS
What is a complication of lumbar puncture
Post lumbar puncture headache: due to decreased ICP. Headache is worse on standing and usually resolves spontanously after 7 days