Local and General ANESTHETICS

Question 1

Esterlinked Local Anethestic

Answer 1

Procaine, Tetracaine, Cocaine, Benzocaine

Question 2

Amide Linked LA (theres an “i” before the caine )

Answer 2

Lignocaine
Mepivacaine
Bupivacaine
Ropivacaine
Prilocaine

Question 3

Local anathestic is divided into________ and ____________

Answer 3

Ester and Amide LA

Question 4

_________ LA linkage is easily broken and _________ isnt

Answer 4

Ester linkage is easily broken, Amide linkage is difficult to break

Question 5

Differences between Amide and Ester LA

Answer 5

Question 6

Local Anathestic exists charged and uncharge form outside the membrane but it is only the __________ form that can enter into the membrane

Answer 6

Uncharged form

Question 7

Once the uncharge form gets into the membrane, they get converted to ________ form?

Answer 7

Cationic form - positive charged ions

Question 8

Which form blocks the Sodium channels?

Answer 8

Cationic form

Question 9

What is the mechanism of Action for Local Anesthetia?

Answer 9

Block conduction by decreasing thr large transient increase in the permeability to Na+

Question 10

True or false in acidic conditions like infection, LA gets converted to acidic form on the surface making it less effective?

Answer 10

True

Question 11

When LA blocks Na channels

Answer 11

There is an INCREASE in threshold of excitability
-impusle conduction slows
- decrease rate of rise of the action potential
- ultimately pevent propagation of action potential

Question 12

True or false: Small fibres are essily blocked than large fibres?

Answer 12

True

Question 13

True or false: Myelinated nerved tend tonbr blocked before unmyelinated nerved of the same diameter?

Answer 13

True

Question 14

What are the order of sensory block? PTTDM

Answer 14

Pain
Temperature
Touch
Deep pressure
Motor

Question 15

After sensory block what is the order of recovery? MDTTP ~ reverse order of sensory function block

Answer 15

Motor
Deep pressure
Touch
Temperature
Pain

Question 16

What is the purpose of adding vasoconstrictors (epinephrine, levonordefrin, norepinephrine) to LA?

Answer 16

Increases the duration of action of LA
Decreases systemic toxicity of LA
Decrease bleeding in the operative field

Question 17

Uses of Local anesthetics

Answer 17

Question 18

Intravenous regional Anesthesia (Bier Block)

Answer 18

Question 19

Toxicity of LAs

Answer 19

Question 20

Where is Spina anethesia given for adults and Children?

Answer 20

Question 21

What are the complications of Spina Anesthesia

Answer 21

Question 22

Epidura Anesthesia

Answer 22

Solution is injected outside of the DURA
And does not go into CSF
Sensation is active below and above the site of injection unlike spinal anethesia

Question 23

Class question

Answer 23

Question 24

Class question

Answer 24

Question 25

Class questions

Answer 25

Question 26

Question

Answer 26

Question 27

Question

Answer 27