Encephalitis

Question 1

Diffused infection of the brain parenchyma almosg invariably associated with meningeal inflammation

Answer 1

Encephalitis
Meningsal inflammation-Meningoencephalitis
With simultaneous involvement of the spinal cord (encephalomyelitis)

Question 2

Endemic Encephalitis is caused by

Answer 2

West nile virus

Question 3

Sporadic Encephalitis is caused by

Answer 3

Herpes Simplex Virus

Question 4

Zoonotic encephalitis is caused by

Answer 4

Rabies

Question 5

What are the symptoms of Encephalitis

Answer 5

Symptoms includes: Headache (mild), Fever (low grade) altered mentation , FOCAL NEUROLOGICAL DEFICIT, seisure, NO SEPSIS

Question 6

What is focal neurological deficit?

Answer 6

Answer

Question 7

Symptoms of encephalitis vary according to the area of the brain affected

Answer 7

Question 8

Symptoms of encephalitis vary according to the area of the brain affected

Answer 8

Question 9

Encephalitis sporadic causal viruses in the US

Answer 9

HSV-1
CMV
Rabies
JcV
HiV
Polio

Question 10

Encephalitis epidemic causal viruses in the US

Answer 10

Question 11

Morphology, Transmission vector, Epidemiology of West Nile virus

Answer 11

Question 12

Infection cascaxde of West Nile disease

Answer 12

Question 13

Pathogenesis of West Nile Dissease

Answer 13

Question 14

Labs for West mile encephalitis

Answer 14

Question 15

Answer 15

Question 16

Answer 16

Question 17

Sensation is alert throughout…He is alert but oriented only to self and year…

Answer 17

Warm climate- Florida and West Nile is endemic
Infection and focal deficit presenting as assymetric weakness, flaccid paralysis, brain and motor neuros. Intact sensation indicates that peripheral nerves are not affected.

Worked as a landscaper (gardener) more chances of getting bitten by insects/mosquitoes and ticks

Question 18

Morphology of HSV encephalitis

Answer 18

Question 19

Transmission of HSV encephalitis

Answer 19

Question 20

HSV remains Latent in _________ ganglion?

Answer 20

Trigeminal Ganglion

Question 21

MOA of Acyclovir - main treatment of HSV encephalitis

Answer 21

A nucleoside analog-
Targets DNA polymerase but requires activation with Viral Thymidine kinase .

Question 22

What aids the virus move to the CNS from they PNS by retrograde?

Answer 22

Dyenin

Question 23

Pathogenesis of HSV encephalitis is mainly on the temporal lobe

Answer 23

Question 24

Neuro imaging of HSV encephalitis involving the prominent temporal lobe

Answer 24

Question 25

What is the Gold standard test for HSV encephalitis?

Answer 25

PCR

Question 26

HSV encephalitis Lab

Answer 26

Question 27

What additional lab value can be given to appropriately diagnose HSV encephalitis?

Answer 27

RBC seen

Question 28

What is the most Common resistance to Acyclovir?

Answer 28

Do not produce the thymidine Kinase so acyclovir does not get activated.

Question 29

Vector that causwles Rabies Encephalitis

Answer 29

Bats

Question 30

If rabies infection reaches the brain, it is 100% fatal- True or false?

Answer 30

True

Question 31

Morphology, transmission vector, epiddmiology of Rabies Encephalitis

Answer 31

Question 32

Rabies can be transferred via?

Answer 32

Question 33

Signs and symptoms of Rabies encephalitis infections

Answer 33

Question 34

Confirm case of Rabies

Answer 34

Question 35

Negri bodies (Eosinophilic cytoplasmic inclusion bodies) are seen in postmortem test of Rabies Encephalitis case. TRUE OR FALSE

Answer 35

True DNA- nucleus RNA- cytoplasm

Question 36

Prevention of the Rabies Encephalitis

Answer 36

Question 37

Flowchart for Encephalitis

Answer 37

Question 38

Flowchart for Encephalitis

Answer 38

Question 39

Other viruses that may also cause encephalitis

Answer 39

Question 40

Inflammation of the meninges surrounding brainband parenchyma

Answer 40

Meningoencephalitis

Question 41

Primary Meningoencephalitis is caused by

Answer 41

Parasitic Amoeba- Brain eating ameoba

Question 42

Which amoeba is the brain eating amoeba? A. Naegleria Fowleri B. acanthamoeba C.Balamuthia

Answer 42

Naegleria Fowleri

Question 43

What are the 3 forms that Free living amoeba can exist in?

Answer 43

Cyst Flagella Amoeba (in tissues)

Question 44

What is the Epidemiology and Reservior

Answer 44

Question 45

Transmissionn and Pathogenesis of Amoeba (fresh eating)

Answer 45

Question 46

Symptoms of primary meningoencephalitis

Answer 46

Question 47

Lab finds

Answer 47

Question 48

Images of Naegleria Trophozoites, Infected Brain Tissue, neagleria trophozoite in CSF

Answer 48

Question 49

Trigger clues, prevention and treatment of Primary meningoencephalitis

Answer 49

Question 50

Granulomatous Amebic Encephalitis Acanthamoeba

Answer 50

Question 51

What is the vector that transmits Lyme disease (Neuroborreliosis)

Answer 51

Ixodes tick

Question 52

Etiology, vector, antibiotics of Neuroborreliosis- Lyme Disease

Answer 52

Question 53

Pathogenesis of Lyme disease

Answer 53

Question 54

Sign symptoms and Labs

Answer 54

Question 55

Classical question for neuroborreliosos (lyme disease)

Answer 55