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cAS3 > Encephalitis > Flashcards

Encephalitis Flashcards

1
Q

Diffused infection of the brain parenchyma almosg invariably associated with meningeal inflammation

A

Encephalitis
Meningsal inflammation-Meningoencephalitis
With simultaneous involvement of the spinal cord (encephalomyelitis)

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2
Q

Endemic Encephalitis is caused by

A

West nile virus

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3
Q

Sporadic Encephalitis is caused by

A

Herpes Simplex Virus

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4
Q

Zoonotic encephalitis is caused by

A

Rabies

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5
Q

What are the symptoms of Encephalitis

A

Symptoms includes: Headache (mild), Fever (low grade) altered mentation , FOCAL NEUROLOGICAL DEFICIT, seisure, NO SEPSIS

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6
Q

What is focal neurological deficit?

A

Answer

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7
Q

Symptoms of encephalitis vary according to the area of the brain affected

A
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8
Q

Symptoms of encephalitis vary according to the area of the brain affected

A
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9
Q

Encephalitis sporadic causal viruses in the US

A

HSV-1
CMV
Rabies
JcV
HiV
Polio

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10
Q

Encephalitis epidemic causal viruses in the US

A
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11
Q

Morphology, Transmission vector, Epidemiology of West Nile virus

A
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12
Q

Infection cascaxde of West Nile disease

A
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13
Q

Pathogenesis of West Nile Dissease

A
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14
Q

Labs for West mile encephalitis

A
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15
Q
A
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16
Q
A
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17
Q

Sensation is alert throughout…He is alert but oriented only to self and year…

A

Warm climate- Florida and West Nile is endemic
Infection and focal deficit presenting as assymetric weakness, flaccid paralysis, brain and motor neuros. Intact sensation indicates that peripheral nerves are not affected.

Worked as a landscaper (gardener) more chances of getting bitten by insects/mosquitoes and ticks

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18
Q

Morphology of HSV encephalitis

A
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19
Q

Transmission of HSV encephalitis

A
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20
Q

HSV remains Latent in _________ ganglion?

A

Trigeminal Ganglion

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21
Q

MOA of Acyclovir - main treatment of HSV encephalitis

A

A nucleoside analog-
Targets DNA polymerase but requires activation with Viral Thymidine kinase .

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22
Q

What aids the virus move to the CNS from they PNS by retrograde?

A

Dyenin

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23
Q

Pathogenesis of HSV encephalitis is mainly on the temporal lobe

A
24
Q

Neuro imaging of HSV encephalitis involving the prominent temporal lobe

A
25
Q

What is the Gold standard test for HSV encephalitis?

A

PCR

26
Q

HSV encephalitis Lab

A
27
Q

What additional lab value can be given to appropriately diagnose HSV encephalitis?

A

RBC seen

28
Q

What is the most Common resistance to Acyclovir?

A

Do not produce the thymidine Kinase so acyclovir does not get activated.

29
Q

Vector that causwles Rabies Encephalitis

A

Bats

30
Q

If rabies infection reaches the brain, it is 100% fatal- True or false?

A

True

31
Q

Morphology, transmission vector, epiddmiology of Rabies Encephalitis

A
32
Q

Rabies can be transferred via?

A
33
Q

Signs and symptoms of Rabies encephalitis infections

A
34
Q

Confirm case of Rabies

A
35
Q

Negri bodies (Eosinophilic cytoplasmic inclusion bodies) are seen in postmortem test of Rabies Encephalitis case. TRUE OR FALSE

A

True

DNA- nucleus
RNA- cytoplasm

36
Q

Prevention of the Rabies Encephalitis

A
37
Q

Flowchart for Encephalitis

A
38
Q

Flowchart for Encephalitis

A
39
Q

Other viruses that may also cause encephalitis

A
40
Q

Inflammation of the meninges surrounding brainband parenchyma

A

Meningoencephalitis

41
Q

Primary Meningoencephalitis is caused by

A

Parasitic Amoeba- Brain eating ameoba

42
Q

Which amoeba is the brain eating amoeba?
A. Naegleria Fowleri
B. acanthamoeba
C.Balamuthia

A

Naegleria Fowleri

43
Q

What are the 3 forms that Free living amoeba can exist in?

A

Cyst
Flagella
Amoeba (in tissues)

44
Q

What is the Epidemiology and Reservior

A
45
Q

Transmissionn and Pathogenesis of Amoeba (fresh eating)

A
46
Q

Symptoms of primary meningoencephalitis

A
47
Q

Lab finds

A
48
Q

Images of Naegleria Trophozoites, Infected Brain Tissue, neagleria trophozoite in CSF

A
49
Q

Trigger clues, prevention and treatment of Primary meningoencephalitis

A
50
Q

Granulomatous Amebic Encephalitis Acanthamoeba

A
51
Q

What is the vector that transmits Lyme disease (Neuroborreliosis)

A

Ixodes tick

52
Q

Etiology, vector, antibiotics of Neuroborreliosis- Lyme Disease

A
53
Q

Pathogenesis of Lyme disease

A
54
Q

Sign symptoms and Labs

A
55
Q

Classical question for neuroborreliosos (lyme disease)

A

cAS3 (17 decks)

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