LO 6 Flashcards
Describe developmental disorders
- A failure during the process of cell division and differentiation into various tissues and structures
- Some may be identified clinically, by radiographic examination, biopsy, or histologic examination
- Inherited disorder - Caused by an abnormality in genetic makeup
- Congenital disorder - Present at birth (May be inherited or developmental); The cause of most congenital abnormalities is unknown
Describe Ankyloglossia (Developmental Soft Tissue Abnormalities)
- An extensive adhesion of the tongue to the floor of the mouth
- Can affect feeding and speech
- Treatment - Frenectomy
Describe Lingual Thyroid (Developmental Soft Tissue Abnormalities)
- A small mass of thyroid tissue located on the tongue
- Results from the failure of the primitive thyroid tissue to migrate from its developmental location in the area of the foramen cecum on the posterior portion of the tongue to its normal position in the neck
- Treatment - It may be removed if it is obstructive, provided the patient has other functioning thyroid tissue
Describe developmental cysts
- An abnormal fluid-filled epithelium-lined sac or cavity
- Most common oral cyst - Radicular cyst (periapical cyst) or Residual cyst
Developmental cysts are classified as __________ or ____________
- Odontogenic
- Nonodontogenic
What information is needed to classify cysts?
- Location
- Cause
- Origin of the epithelial cells
- Histologic appearance
Describe developmental cysts’ relationship to bone and soft tissue
- They can cause expansion of bone
- Intraosseous cysts: Occur within bone
- Extraosseous cysts: Occur in soft tissue
- Cysts within bone generally appear as well-circumscribed radiolucencies
- They may appear as unilocular or multilocular
Describe Odontogenic: Dentigerous
Cysts (Follicular Cysts)
- Forms around the crown of an unerupted or developing tooth
- The epithelial lining originates from the reduced enamel epithelium after the crown has formed and calcified
- Most commonly occurs around the crown of an unerupted or impacted third molar
- Radiographic - A well-defined, unilocular radiolucency around the crown of an unerupted or impacted tooth
- Histologic - The lumen is most characteristically lined with cuboidal epithelium surrounded by a wall of connective tissue
- Treatment - Removal of the cyst (There is some risk of cystic transformation into a neoplasm)
Describe an odontogenic eruption cyst
- Similar to a dentigerous cyst
- Found in the soft tissue around the crown of an erupting tooth
- Occurs only on primary teeth, fairly common
- Pain associated with inflammation only, very small risk of infection
- No treatment
Describe an odontogenic Primordial Cyst
- Develops in place of a tooth
- Most commonly in place of a third molar
- Most often seen in young adults and discovered on radiographic examination
- Histology - The lumen is lined by stratified squamous epithelium surrounded by parallel bundles of collagen fibers; It may prove to be an odontogenic keratocyst or a lateral periodontal cyst
- Treatment - Surgical removal; The risk of recurrence depends on the diagnosis
Describe a Keratocyst (OKC)
- Histology - The lumen is lined by epithelium; Most often seen in the mandibular third molar region
- Can move teeth and cause resorption
- Treatment - Because of the high recurrence rate, surgical excision and osseous curettage are recommended
- Radiographic - Frequently appears as a well-defined, multilocular, radiolucent lesion; High recurrence rate!
Describe a Calcifying Odontogenic Cyst (COC)
- A nonaggressive, cystic lesion lined by odontogenic epithelium
- Closely resembles an ameloblastoma
- Has a characteristic feature called ghost cells
Describe a Lateral Periodontal Cyst
- Lateral periodontal cyst is most often seen in the mandibular cuspid and premolar area
- It is an asymptomatic, unilocular or multilocular radiolucent lesion on the lateral surface of a tooth root
- Botryoid odontogenic cyst = multilocular variant of lateral periodontal cyst
- Lateral periodontal cyst is found most often in males
- Histology - A gingival cyst has the same type of lining as the lateral periodontal cyst but is located in the soft tissue; A thin band of stratified squamous epithelium lines the gingival cyst
- Treatment - Surgical excision
Describe Glandular Odontogenic Cysts (GOC)
- Microscopic appearance: Multicystic lesions
- Eosinophilic cuboidal cells on the surface of the epithelium
- Columnar cells with cilia
- Intraepithelial microcysts
- Affects males and females
- Most common 50-59 years
- Appears similar to ameloblastoma or odontogenic keratocyst (OKC)
- High recurrence rate
Describe Nasopalatine Canal Cyst (Incisive Canal Cyst)
- Located within the nasopalatine canal or the incisive papilla
- More common for males
- 40-60 years old
- Usually asymptomatic
- May see a small, pink bulge near the apices and between the roots of the maxillary central incisors on the lingual surface
- Radiographic - A well-defined, radiolucent lesion; May be oval or heart-shaped
- Histology - Lined by epithelium varying from stratified squamous to pseudostratified ciliated columnar epithelium; Client might have salty taste
- Treatment - Surgical excision
Describe a Median Palatine Cyst
- A well-defined, unilocular radiolucency
- Located in the midline of the hard palate
- Histology - Lined with stratified, squamous epithelium surrounded by dense fibrous connective tissue
- Treatment - Surgical removal
Describe Nasolabial Cysts
- A soft tissue cyst
- Thought to originate from the lower anterior portion of the nasolacrimal duct
- Observed in adults 40 to 50 years of age
- 4:1 ratio in favor of females
- Clinical - An expansion or swelling in the mucobuccal fold in the area of the maxillary canine and the floor of the nose
- Histology - Lined with pseudostratified, ciliated columnar epithelium and multiple goblet cells
- Treatment - Surgical excision
Describe Lymphoepithelial Cysts
- Most commonly found in major salivary glands
- A stratified squamous epithelial lining surrounded by a well-circumscribed component of lymphoid tissue
- Appears to arise from epithelium trapped in a lymph node during development
- Most commonly found intraorally on the floor of the mouth and the lateral borders of the tongue
- Appears as a pinkish-yellow raised nodule
- Treatment - Surgical excision
Describe Epidermal Cysts
- A raised nodule on the skin of the face or neck
- May be noted intraorally on occasion
- Histology - Lined by keratinizing epithelium that resembles the epithelium of the skin; The lumen is usually filled with keratin scales
- Treatment - Surgical excision
Describe Dermoid Cysts
- A developmental cyst often present at birth or noted in young children
- It is usually found on the floor of the mouth when it is located in the oral cavity
- May cause tongue displacement
- May have a doughy consistency when palpated
Describe Thyroglossal Tract (Duct) Cysts
- Forms along the tract the thyroid gland follows in development
- Found in young individuals (<20 years of age)
- No sex predilection
- Treatment - Excision of the cyst and tract
Describe Globulomaxillary Cysts
- A well-defined, pear-shaped radiolucency
- Located between the roots of the maxillary lateral incisor and cuspid
- Treatment - Surgical removal
Describe Pseudocysts
- Not true cysts because they are not lined by epithelium
- Static bone cyst
- Simple bone cyst
- Aneurysmal bone cyst
Describe Stafne Defect
- A pseudocyst
- Not a pathologic cavity
- Clinically: An anatomic depression on the posterior lingual area of the mandible
- No treatment
- A well-defined, cystlike radiolucency