Liver/Pancrease/PKU Flashcards
clotting factor, cholesterol, glucose is made by
liver
Hepatic encephalopathy is treated with
lactulose or Dialysis
liver failure leads to
bleeding, clotting risk, hyperbilirubinemia (RBC breakdown)
Acute viral hep A/E tx
short, self limiting, vaccinate
Chronic Hep B (sex) linked with? Tx?
HCC
Peg interferon and liver transplant
Hep C is tx with
Ledipasvir (harvani) and sfosbuvir (sovaldi)
Hep D treated with
Hep B
NASH leads to
Cirrhosis and HCC, risk with APAP
Cirrhosis main risk is
EtOH
Cirrhosis presents with
jaundice, anorexia, caput medusa, high Cr, low urine output, Portal HTN, Hepatorenal syndrome (liver transplant)
HCC main risks
Hep B and C, NASH
Acute pan presents with
N/V fever, jaundice, Cullen, Grey Turner.
Acute pancreatitis triggers
Gallstone or EtOH
Diag of Acute pancreattis
left shift, high amylase, lipase, US and CT (sential loop)
How do you treat Acute Pancreatitis?
NPO, stop EtOH, surgery to remove block
Chronic Pancreatitis is due to
Stone or EtOH, need to remove stone
Diag chronic pancreatitis
CT - lakes
Tx of chronic pancreatitis?
Whipple
Pancreatic cancer diag?
CT, CA 19-9 and CEA. mostly at the head
Amino acid in infants disorders are (3)
PKU, homocysteine, Maple syrup urine.
PKU is auto res, and tx is?
No aspartane (pku)
PKU presents as
fair skin, musty smell, epilepsy, parkinsonism
PKU is diagnosed?
PKU levels, and MRI
What hep has the highest risk of chronicdisease?
Hep C
HBeAg serologic marker for hepatitis B indicate?
Replication and infectivity.
Portal HTN can be treated with>
Spironolactone
Spontaneous bacterial peritonitis is treated with
Cefotaxime - ecoli
What presents with lipidemia and high alk phose?
Primary biliary cholangitis
Which of the following is a common cause of worsening hepatic encephalopathy?
Constipation
When do you give cefoxetine to a patient with ascites?
ascitic neutrophil count > 250 cells.
What antibiotic is best known for causing aplastic anemia?
Chloramphenicol
and acute hepatitis
mcc of adult rectal bleeding is
Hemorrhoids
If refractory, or if symptoms are severe, or if the internal hemorrhoid is strangulated, what do you do for hemorroids?
Oper hemorrhoidectomy.
How do you diagnose HCV?
RNA PCR test