Liver function Flashcards
what are the types of liver disease
infection toxic autoimmune biliary tract obstruction vascular metabolic neoplastic
what is intrahepatic cholestasis
problems secreting bile by hepatocytes
what is extra hepatic cholestasis
problems with outflow of bile
what type of bilirubin accumulates in cholestasis
conjugated
urine darkens and stools become lighter
what type of jaundice do you get unconjugated bilirubin
pre hepatic
bilirubin is not found in the urine
what are common causes of chronic liver disease
alcoholic liver
chronic active hepatitis
primary biliary cirrhosis
what does ALT and AST show
liver cell damage
what does bilirubin show
cholestasis
what does ALP and GGT show
biliary epithelial damage and obstruction
what does albumin show
synthetic function
what is bilirubin
breakdown product of haemoglobin
what further investigations can be done after LFTs
alpha one anti trypsin alpha feto protein copper studies hepatitis serology iron studies autoantibodies radiology liver biopsy
