Clinical chemistry Flashcards
what thyroid hormones would be found in primary hyperthyroidism
low TSH (ant pit) high T3 and T4
what thyroid hormones would be found in primary hypothyroidism
high TSH
low T4
what is primary hyperthyroidism
pathology is within the thyroid gland
where do carbonic anhydrase inhibitors act
PCT
where do loop diuretics act
loop of henle
where do thiazide directs act
DCT
where do potassium sparing diuretics act
collecting duct
what is creatinine
breakdown product of muscle
excreted by kidneys
good marker of kidney function
what does a raised creatine suggest
glomerular filtration has reduced to less than 50%
what does a raised urea and creatine suggest
dehydration and poor renal blood flow (pre renal impairment)
or renal failure
what is acute tubular necrosis
lack of blood flow to the kidneys causes necrosis of cells
what might cause post renal impairment
an obstruction e.g. BPH
Describe the rise in creatinine and urea in intra renal failure
the rise in creatinine is greater than the rise in urea
describe the rise in creatinine and urea in pre renal failure
the rise in urea is greater than the rise in urea
