Jaundice Flashcards

1
Q

name the cardiac markers

A

troponin T and I

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2
Q

what is CRP

A

marker of acute illness; infection

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3
Q

what is ESR

A

non specific indicator of disease

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4
Q

what does a liver panel consist of

A
bilirubin
enzymes
ALT, GGT, ALP
albumin
clotting
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5
Q

what organ creates albumin

A

liver

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6
Q

what is normal bulirubin

A

2-20 micromols

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7
Q

when is jaundice clinically detectable

A

40-50 mmols

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8
Q

what enzyme is associated with hepatocellular jaundice

A

ALT

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9
Q

what enzyme is associated with cholestatic jaundice

A

ALP

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10
Q

what is prehepatic jaundice

A

excess bilirubin production
haemolysis
rhabdomyolysis

causes unconjugated bilirubin

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11
Q

what is the main liver enzyme

A

ALT

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12
Q

what would the liver panel be in hepatocellular jaundice

A

increase bilirubin

increase ALT

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13
Q

What enzyme is stimulated by some drugs and alcohol

A

GGT

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14
Q

what enzymes are found in post hepatic or cholestatic jaundice

A

high ALP and GGT

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15
Q

What enzyme is a marker of bone disease

A

ALP

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16
Q

what type of jaundice would you have dark urine

A

cholestatic

17
Q

what are the two types of cholestatic jaundice

A

intrahepatic cholestasis (tumour, drugs, viruses)

extrahepatic cholestasis
gallstones, pancreatic ca, billiard tract ca

18
Q

what would the liver panel be in cholestatic jaundice

A

raised ALP
ALT moderately raised
dark urine