Liver Day 3 Flashcards

1
Q

Hepatic metabolic functions of the liver: carbs

A

Converts excess sugar to glycogen
If there is lack of sugar it converts glycogen into glucose

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2
Q

Hepatic metabolic functions of the liver: fats

A

Converts stored fat into energy
Yeilding glc and cholesterol etc
Converts hepatocytes into lipoproteins

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3
Q

Hepatic metabolic functions of the liver: protein

A

Forms many plasma proteins like albumin and fibrinogen
Converts amino acids to fatty acids and urea

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4
Q

Digestive function of the liver

A

Secretes bile and bilirubin in the bile

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5
Q

Storage function of the liver

A

Stores iron and vitamins

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6
Q

Detox function of the liver

A

Detoxes the liver from alcohol poison drugs and hormones

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7
Q

What does albumin do

A

Draws water into the vascular system from tissue spaces

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8
Q

What does fibrinogen do

A

Helps with the process of blood clotting

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9
Q

What are enzymes

A

Protein catalysts

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10
Q

What does B.U.N

A

Measures the amount of urea in blood

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11
Q

Process of the bilirubin detox

A
  1. Seperates from albumin
  2. Combines with 2 glucuronide molecules
  3. Then actively transported across the cell membrane into bile canaliculi
  4. Lastly the bile duct receives it and deliver it to the bowel to be excreted in feces
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12
Q

What is bile

A

Excretory product of the liver

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13
Q

What does bile do

A

Emulsifies fat and excretes liver wastes products

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14
Q

Components of bile

A

Water, bile salts, and bile pigment

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15
Q

What does bile salts do

A

Helps with vitamin absorption

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16
Q

What do the liver functions tests demonstrate

A

How the liver is functioning in normal and/or abnormal conditions

17
Q

What are the 7 liver functions test

A
  1. AST
  2. ALT
  3. Prothrombin time
  4. LDH
    5.Bilirubin
  5. Alk Phos
  6. Albumin/Globulins
18
Q

What is AST? When do we find high values of it?

A

A enzyme present in tissues with high metabolic activity
If there is high levels in blood that means that the tissue it is in is either dead or damaged (disease present)

19
Q

What does lactic acid dehydrogenase (LDH) show? Where is it present

A

Shows a probable myocardial infarction or pulmonary infarction if in high values
Present in lungs, sk m, heart, kidney, brain, amd liver

20
Q

Where is alkaline phosphatase produced? What does it indicate

A

By placenta, bone, liver and intestines
High levels show possible obstruction, abcess, carcinoma, or cirrhosis

21
Q

Why is there a high level of bilirubin

A

Excess rbc destruction
Malfunction if liver cells
Blockage of ducts leading to cells

22
Q

What is prothrombin time? What does high levels indicate?

A

Its a liver enzyme important for blood clotting
Increase levels probable liver disease with cellular damage

23
Q

Albumin/globulin levels effects

A

Decreased levels = decreased protein synthesis which can lead to metabolic derangement of liver