Liver Flashcards

1
Q

Why does the Liver look brown?

A

As it contains lots of mitochondria

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2
Q

What is the name of the ligament that separates the 2 lobes of the liver?

A

Falciform ligament

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3
Q

What blood vessel does blood from the GI tract travel to the liver by?

A

Hepatic portal Vein

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4
Q

What blood vessel deliverers oxygenated blood to the liver?

A

Hepatic artery

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5
Q

What blood vessel leaves the liver to return to the heart?

A

Hepatic Vein

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6
Q

Where is bile stored?

A

Gall bladder

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7
Q

What hormone causes the release of bile from the gall bladder?

A

CCK

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8
Q

What is a portal system?

A

Where blood passes through 2 capillary sets before returning to the heart

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9
Q

Name 2 portal systems in the body

A

Hepatic portal system and hypothalamo-hypophyseal portal system

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10
Q

In the hepatic portal system, where is the first capillary bed found?

A

GI tract

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11
Q

What travels in the hepatic portal Vein?

A

Water, carbohydrates, proteins, hormones, electrolytes, toxins

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12
Q

Where is ammonia broken down?

A

Liver

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13
Q

What is ammonia broken down into?

A

Urea

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14
Q

What doesn’t travel in the portal system?

A

Lipids

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15
Q

How are lipids absorbed in the digestive system?

A

They are taken into cell and processed in chylomicrons. These are then taken up by lymphatic vessels called lacteals in microvilli

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16
Q

Give 4 functions of the liver

A

Storage, bile production, detoxification, metabolism

17
Q

What molecules are produced in the liver

A

Plasma proteins(albumin), glycogen and coagulation factors

18
Q

What is stored in the liver

A

Iron, vitamin A, vitamin B12, Vitamin D, vitamin K and glycogen

19
Q

What is broken down in the liver?

A

Drugs, hormones, poisons and haemoglobin

20
Q

What type of cells are present in the liver that have a phagocytic function?

A

Kupffer cells

21
Q

Give an example of the exocrine function of the liver

A

Bile is produced and transported out via duct

22
Q

Give an example of the endocrine function of the liver

A

It produces angiotensinogen and secretes it into the blood

23
Q

What is the most common cell found in the liver

A

Hepatocytes

24
Q

What is the function of hepatocytes?

A

Involved in bile production

25
Q

What is a sinusoid?

A

A tubular space for the passage of blood from the hepatic portal Vein and hepatic artery to the hepatic Vein.

26
Q

What is different about the endothelial cells lining the sinusoid?

A

There are large gaps between cells

27
Q

What is the portal triad composed of?

A

Bile duct, hepatic portal Vein and hepatic artery

28
Q

What is the liver acinus?

A

The functional unit of the liver

29
Q

Where are stellate cells found?

A

In the space of disse

30
Q

What do stellate cells contain?

A

Vitamin A granules

31
Q

What affect does cirrhosis have on stellate cells?

A

Lose their ability to store vitamin A and then different into myofibroblasts and start depositing collagen. The collagen can surround the central Vein causing hypertension and fill the sinusoids.

32
Q

Where are kupffer cells found?

A

Lining the sinusoids