Lit Misc (Ophtho, Derm, Repro etc)

Question 1

What dog breed is predisposed to uveodermatologic syndrome? What ocular changes are commonly noted with UDS? What is the prognosis for vision, and associated risk factors are associated with visual prognosis?

Answer 1

Zarfoss JAVMA 2018
Akitas (4.1% affected), possibly Huskies & Samoyeds.
Bilateral panuveitis > 36% glaucoma, 57% bilaterally blind.
50% dogs had vision initially or regained vision during FU period.
Median time to blindess = 13.5mths. No risk factors identified with visual px in this study.

Question 2

What diseases may be associated with acute erythroderma in dogs? What was a distinct histologic feature of these skin lesions?

Answer 2

Cain JAVMA 2017
GI disease (hematochezia, V+)

Inflammatory bowel disease, pancreatitis, adverse
food reaction, cause unknown for 40% dogs
Eosinophilic granules (within Mp or granulocyte cytoplasm)

Question 3

Which 2 hormones are present in dogs with ovarian remnant syndrome, and where are they normally expressed?

Answer 3

Place JAVMA 2019
- Anti-Mullerian hormone (AMH) - expression is limited to the granulosa cells of ovarian follicles.
- Progesterone (P4) - secreted by corpora lutea into circulation

Question 4

What induction/anaesthetic protocol was associated with higher post-anaesthetic complication rate in brachycephalic dogs?

Answer 4

Gruenhied JAVMA 2018
Ketamine + BZD (cf propofol)