liquid dosage Flashcards
fungi organisms eukaryotic or prokaryotic?
Eukaryotic
two main types of fungi?
moulds and yeasts
what does it mean by “fungi are carbon heterotrophs?”
they required pre formed organic compounds as carbon sources
common symptoms of tinea infections (caused by moulds)
itching, burning, pain, irritations.
what Ringworm infections?
no worm involved, it’s an infection it can affect the skin, groin and scalp
How is Ringworm treated?
topical anti fungal i.e. imidazole, clotrimazole..
Oral therapy if topical fails/immunocompromised; i.e terbinafine,itraconzole
How is ringworm treated in the scalp?
difficult treatment
you use topical shampoos, to stop the spread, and anti fungi.
What is empirical treatment?
we treat a patient based on our best knowledge until the sensitively test come back…
What is the first antifungal agent (one of the oldest)
Griseofulvin has a low
Why is Griseofulvin not used as commonly anymore?
has a low therapeutic window..
short half life
less lipophilic
Side effects of Griseofulvin?
cognitive side effects include dizziness, confusion, fatigue, sleep disturbances…
what is the cause Tinea Pedis (athlete’s foot)?
caused by fungi infection
causative species include
Trichophyton Rubrum
trichophyton Mentagrophytes
what are the symptoms of Tinea PEDIS?
skin becomes scaled, macerate and fissuring. Moccasin type (the skin will appear drier) less common
How do you treat athlete’s foot (tinea pedis)
Imidazole cream
terbinafine cream
if inflammation combine with hydrocortisone.
if Topical fails or serve infection oral treatment: Terbinafine
how is terbinafine a better anti fungi drug than.
lipophilic drug
higher half life
