Lipoprotein:

Question 1

Lipoprotein composition

Answer 1

• Nonpolar lipids (ie. Triacyglycerol and Cholesterol ester0
• amphipathic lipids (ie. cholesterol and Phospholipids)
• Proteins

Question 2

Structure of lipoprotein?

Answer 2

• Non polar core
• Single layer of amphipathic lipid
• Lipoprotein is a complex of: TAG, cholesterol, cholesterol esters, phospholipids, and apo lipoprotein

Question 3

Lipoprotein density is dependent on —

Answer 3

Apo-lipoprotein content

Question 4

The higher the Apo lipoprotein content

the higher the_____

Answer 4

density

Question 5

Lipoprotein size is dependent on _____

Answer 5

Triglyceride content
( Higher TAG= Bigger SIZE)

Question 6

What do each of the following carry?

• Chylomicron
• VLDL
• IDL
• LDL
• HDL

Answer 6

Chylomicron= Triglycerides
VLDL= Triglycerides
IDL= triglycerides/Cholesterol
LDL= Cholesterol 
HDL= Cholesterol/Phospholipids

Question 7

Lipoprotein is classified according to?

Answer 7

• Densities (separated by ultracentrifugation)

- Electrophoretic Mobility

Question 8

Separation of plasma lipoprotein by ultracentrifugation? ( in order?)

Answer 8

• Chylomicron
• VLDL
  LDL
  HDL
  Albumin

Question 9

Separation of plasma lipoproteins on the basis of their electrophoretic mobility

Answer 9

From cathode to Anode?
- Chylomicron
- LDL (B- lipoprotein)
-VLDL ( Pre-B-lipoprotein)
HDL (alpha- lipoprotein)