lipoglycopeptides, lipopeptides, and oxazolidinones

Question 1

telavancin activity

Answer 1

active against most gram + bacteria including strep, enterococci (not so much VRE), and staph (including MRSA)

Question 2

dalbavancin and oritavancin half life

Answer 2

long acting IV lipoglycopeptides with t1/2 > 200 hours and expensive

Question 3

dalbavancin and oritavancin indications

Answer 3

SSTI

Question 4

lipoglycopeptide clinical pearl

Answer 4

need ID consult and unique circumstance in order for it to be prescribed

Question 5

drug class of daptomycin and route

Answer 5

lipopeptide and comes in IV

Question 6

daptomycin activity

Answer 6

staph (including MRSA), strep, enterococci(including VRE)

Question 7

daptomycin indication

Answer 7

MRSA, VRE (SSTI, UTI, bone/joint, bacteremia)

Question 8

when should you avoid daptomycin

Answer 8

pneumonia (inactivated by lung surfactant) and CNS infections because it cannot cross

Question 9

oxazolidinone drugs

Answer 9

linezolid and tedizolid

Question 10

oxazlidinone activity

Answer 10

gram positive (same as daptomycin) with staph (including MRSA), strep, and entercocci (including VRE)