Lipids Metabolism (FA oxidation) Flashcards
1
Q
Catabolism of fatty acids
A
- Occurred at mitochondria
- Produce acetyl-CoA
- NADH & FADH2 is the reducing power
2
Q
Anabolism of fatty acids
A
- Occurred at animal cytosol and plant chloroplast
- Start as a condensation of malonyl-CoA and acetyl-CoA
- NADPH is the reducing power
3
Q
Fatty acid Oxidation
A
3 types (B , A , W)
4
Q
Beta oxidation
A
Major pathway → mitochondria
Produce acetyl & propinoyl co A
Successive removal of 2 carbon atoms (acetyl co A).
5
Q
Alpha oxidation
A
Alternative (brain) minor path way
6
Q
Omega oxidation
A
ER, Succinvl COA
7
Q
Minor & major oxidation pathways
A
eliminate toxic level FA
8
Q
Beta oxidation pri steps
A
Activation & transportation
9
Q
Beta oxidation Occurs in .. steps
A
4
oxidation - Hydration - oxidation - Splitting
10
Q
Complete Beta oxidation
A
a- formation acetyl coA & NADH & FADH2
B- oxidation acetyl co A …TCA cycle to CO2 & H2O