Lipids Metabolism (FA oxidation) Flashcards

1
Q

Catabolism of fatty acids

A
  • Occurred at mitochondria
  • Produce acetyl-CoA
  • NADH & FADH2 is the reducing power
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2
Q

Anabolism of fatty acids

A
  • Occurred at animal cytosol and plant chloroplast
  • Start as a condensation of malonyl-CoA and acetyl-CoA
  • NADPH is the reducing power
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3
Q

Fatty acid Oxidation

A

3 types (B , A , W)

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4
Q

Beta oxidation

A

Major pathway → mitochondria

Produce acetyl & propinoyl co A

Successive removal of 2 carbon atoms (acetyl co A).

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5
Q

Alpha oxidation

A

Alternative (brain) minor path way

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6
Q

Omega oxidation

A

ER, Succinvl COA

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7
Q

Minor & major oxidation pathways

A

eliminate toxic level FA

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8
Q

Beta oxidation pri steps

A

Activation & transportation

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9
Q

Beta oxidation Occurs in .. steps

A

4
oxidation - Hydration - oxidation - Splitting

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10
Q

Complete Beta oxidation

A

a- formation acetyl coA & NADH & FADH2
B- oxidation acetyl co A …TCA cycle to CO2 & H2O

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