Lipids Metabolism (Digestion)

Question 1

Lipids Functions

Answer 1

Precursors of hormones
It helps in digestion
It provides store of energy
it provides metabolic fuel
This is part of cell membrane

Question 2

Utilization of Lipids (TAG)

Answer 2

1- Digestion
2- Solubilization
3- Absorption
4- Formation Lipoproteins

Question 3

Fat digestion

Answer 3

1- Emulsification (Mechanically & Chemically)
2- Enzymatic digestion

Question 4

Emulsification

Answer 4

↑ Surface area by ↓ Surface tension

Large molecules into smaller ones

inside enterocyte (Micelles)

Liberation bile salts back to liver

Question 5

Function of Bile salts

Answer 5

1. Digestion of lipids
2. Choleretic action
3. Antiputrefactive action
4. Buffer action
5. Prevention of cholesterol stone

Question 6

Explain how bile salts have a role in digestion of lipids

Answer 6

Activate Raw pancreatic lipase

Question 7

Bile salts hydro nature

Answer 7

Hydrophilic

Question 8

Choleretic action of bile salts

Answer 8

↑ Bile salts production from liver

Question 9

Pancreatic lipase end product

Answer 9

2 FA
2 - MAG

Question 10

Lingual lipase

Answer 10

pH : 5 – 5.5

Question 11

Gastric lipase

Answer 11

pH : 5 – 7
Action in Childs , Vegans

Question 12

Why Gastric lipase doesn’t have action in adults ?

Answer 12

Gastric lipase optimum pH : 5 - 7
Gastric pH in adults : 2

Question 13

Pancreatic lipase

Answer 13

pH : 8

Propancreatic lipase

Acts on (1,3 α carbons)

72% → 2 monoglycerides
6% → 1 monoglycerides
22% → Glycerol + FFA … to circulation esp. short chain FA

Question 14

Pancreatic lipase Acts on ….

Answer 14

(1,3 α carbons)

Question 15

Most active and Main lipases

Answer 15

Pancreatic lipase

Question 16

Digestion Steps

Answer 16

Chewing (M) → Lingual lipase → Stomach contraction (M) → Gastric lipase → Intestine (M) → Bile salts → Pancreatic lipase

Question 17

Steatorrhea

Answer 17

Increase fat content of faces above 5 g / day

Question 18

Steatorrhea causes

Answer 18

1- Damage pancreatic lipase
2- Problem in bile salts

Question 19

…… caused by damage of pancreatic lipase

Answer 19

only steatorrhea

Question 20

…… caused by Problem in bile salts

Answer 20

Steatorrhea & Def fat soluble vitamins

Question 21

To digest lipids completely by pancreatic lipase

Answer 21

Mutase enzyme convert FA from position C2 to C1 or C3