Lipids and CV Disease (BOARD REVIEW) Flashcards

1
Q

What is the minimum desirable level of total cholesterol?

A
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2
Q

What is the minimum desirable level of total cholesterol?

A
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3
Q

What is the clinical stigmata of high cholesterol?

A

Xanthelasma, Xanthomas, Corneal arcus

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4
Q

What is a Xanthelasma?

A

Cholesterol fatty deposits under/around the eyes

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5
Q

What are Xanthomas?

A

Cholesterol deposits on ankles, skin

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6
Q

When should you screen men with no increased risk?

A

35

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7
Q

When should you screen men with increased risks?

A

20-35

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8
Q

When should you screen women with no increased risk?

A

45

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9
Q

When should you screen women with increased risks?

A

20-45

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10
Q

According to OLD standard, optimal LDL is? Borderline high is? High is? Very high is?

A

190

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11
Q

According to OLD standard, desirable total cholesterol is? Borderline high is? High is?

A

240

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12
Q

HDL cholesterol below ? is low?

A

40

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13
Q

HDL cholesterol above ? is high?

A

60

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14
Q

Normal triglycerides?

A
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15
Q

High triglycerides?

A

200-499

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16
Q

What is the PRIMARY aim of therapy?

A

To reach LDL goal, manage weight, increase physical activity

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17
Q

A good rule of thumb for managing cholesterol is…

A

Once you reach your LDL goal, if triglycerides are still >200, work to get NON HDL cholesterol down to 30 higher than LDL goal.

18
Q

When you see a tendonous xanthoma…think…

A

Familial hypercholesterolemia

19
Q

What is the clinical stigmata of high cholesterol?

A

Xanthelasma, Xanthomas, Corneal arcus

20
Q

What is a Xanthelasma?

A

Cholesterol fatty deposits under/around the eyes

21
Q

What are Xanthomas?

A

Cholesterol deposits on ankles, skin

22
Q

When should you screen men with no increased risk?

A

35

23
Q

When should you screen men with increased risks?

A

20-35

24
Q

When should you screen women with no increased risk?

A

45

25
Q

When should you screen women with increased risks?

A

20-45

26
Q

According to OLD standard, optimal LDL is? Borderline high is? High is? Very high is?

A

190

27
Q

According to OLD standard, desirable total cholesterol is? Borderline high is? High is?

A

240

28
Q

HDL cholesterol below ? is low?

A

40

29
Q

HDL cholesterol above ? is high?

A

60

30
Q

Normal triglycerides?

A
31
Q

High triglycerides?

A

200-499

32
Q

What is the PRIMARY aim of therapy?

A

To reach LDL goal, manage weight, increase physical activity

33
Q

A good rule of thumb for managing cholesterol is…

A

Once you reach your LDL goal, if triglycerides are still >200, work to get NON HDL cholesterol down to 30 higher than LDL goal.

34
Q

When you see a tendonous xanthoma…think…

A

Familial hypercholesterolemia

35
Q

What are 3 types of drugs that can cause secondary hyperlipidemia?

A

Estrogen/progestins, protease inhibitors, anabolic steroids

36
Q

What conditions cause secondary hyperlipidemia?

A

Diabetes, HYPOthyroidism, obstructive liver disease/biliary cirrhosis, renal disease

37
Q

Goal of therapy for LDL

A
38
Q

Risk factors for CHD

A

Age (M>45, W>55), smoking, HTN, HDL

39
Q

What counts as a NEGATIVE risk factor when assessing risks?

A

HDL > 60

40
Q

What is the name for the scoring system?

A

Framingham

41
Q

What would you do? A pt with 2+ risk factors and a 10 year risk of

A

LDL of

42
Q

What would you do? A pt with 0-1+ risk factor? What is the LDL goal? When would you initiate lifestyle changes? When would you consider a drug?

A

LDL of