Lipids and CV Disease (BOARD REVIEW) Flashcards
What is the minimum desirable level of total cholesterol?
What is the minimum desirable level of total cholesterol?
What is the clinical stigmata of high cholesterol?
Xanthelasma, Xanthomas, Corneal arcus
What is a Xanthelasma?
Cholesterol fatty deposits under/around the eyes
What are Xanthomas?
Cholesterol deposits on ankles, skin
When should you screen men with no increased risk?
35
When should you screen men with increased risks?
20-35
When should you screen women with no increased risk?
45
When should you screen women with increased risks?
20-45
According to OLD standard, optimal LDL is? Borderline high is? High is? Very high is?
190
According to OLD standard, desirable total cholesterol is? Borderline high is? High is?
240
HDL cholesterol below ? is low?
40
HDL cholesterol above ? is high?
60
Normal triglycerides?
High triglycerides?
200-499
What is the PRIMARY aim of therapy?
To reach LDL goal, manage weight, increase physical activity
A good rule of thumb for managing cholesterol is…
Once you reach your LDL goal, if triglycerides are still >200, work to get NON HDL cholesterol down to 30 higher than LDL goal.
When you see a tendonous xanthoma…think…
Familial hypercholesterolemia
What is the clinical stigmata of high cholesterol?
Xanthelasma, Xanthomas, Corneal arcus
What is a Xanthelasma?
Cholesterol fatty deposits under/around the eyes
What are Xanthomas?
Cholesterol deposits on ankles, skin
When should you screen men with no increased risk?
35
When should you screen men with increased risks?
20-35
When should you screen women with no increased risk?
45
When should you screen women with increased risks?
20-45
According to OLD standard, optimal LDL is? Borderline high is? High is? Very high is?
190
According to OLD standard, desirable total cholesterol is? Borderline high is? High is?
240
HDL cholesterol below ? is low?
40
HDL cholesterol above ? is high?
60
Normal triglycerides?
High triglycerides?
200-499
What is the PRIMARY aim of therapy?
To reach LDL goal, manage weight, increase physical activity
A good rule of thumb for managing cholesterol is…
Once you reach your LDL goal, if triglycerides are still >200, work to get NON HDL cholesterol down to 30 higher than LDL goal.
When you see a tendonous xanthoma…think…
Familial hypercholesterolemia
What are 3 types of drugs that can cause secondary hyperlipidemia?
Estrogen/progestins, protease inhibitors, anabolic steroids
What conditions cause secondary hyperlipidemia?
Diabetes, HYPOthyroidism, obstructive liver disease/biliary cirrhosis, renal disease
Goal of therapy for LDL
Risk factors for CHD
Age (M>45, W>55), smoking, HTN, HDL
What counts as a NEGATIVE risk factor when assessing risks?
HDL > 60
What is the name for the scoring system?
Framingham
What would you do? A pt with 2+ risk factors and a 10 year risk of
LDL of
What would you do? A pt with 0-1+ risk factor? What is the LDL goal? When would you initiate lifestyle changes? When would you consider a drug?
LDL of
