ABX - Side Effects

Question 1

PCN 2

Answer 1

Nephrotoxicity. Allergic reaction and anaphylaxis

Question 2

Ampicillin 2

Answer 2

Maculopapular rash in pts with mono. Diarrhea

Question 3

Cephs 1

Answer 3

Cross reactivity with PCNs

Question 4

What is nice about Aztreonam?

Answer 4

No cross reactivity with PCN’s or Cephs

Question 5

Vancomycin 3

Answer 5

Red man’s syndrome (histamine release when infused too rapidly causing flushing.) Ototoxicity and nephrotoxicity

Question 6

Macrolides

Answer 6

Prolonged QT. Ototoxicity. Good alternative to PCN in allergic patients. GI upset

Question 7

Ototoxicity

Answer 7

Macrolides, vancomycin

Question 8

Fleuroquins

Answer 8

Tendon rupture (Don’t give to children

Question 9

QT prolongation

Answer 9

Macrolides, Fleuroquins.

Question 10

Clindamycin

Answer 10

C diff!!! Not very good CSF penetration. Penetrates your bowels but not your brain:)

Question 11

Tetracyclines

Answer 11

Teeth discoloration. No kids

Question 12

No kids

Answer 12

Tetracyline

Question 13

No people

Answer 13

Fleuroquin

Question 14

Not with dairy

Answer 14

Tetracyclines

Question 15

Sulfonamides.

Answer 15

Rash. No in 2nd trimester pregnancy. Kernicerus. Can cause hemolysis in G6PD deficiency

Question 16

No in pregnancy

Answer 16

Fleuroquins, tetracyclines, sulfas (2nd trimester)

Question 17

What do you want to council people about with metronidazole

Answer 17

No ETOH within first 48 hours. Causes a disulfiram reaction. May cause neurotoxicity.

Question 18

Most common PCN associated with dia-loose?

Answer 18

Augmentin

Question 19

Photosensitivity

Answer 19

Tetracyclines, fluoroquins, sulfa, pyrazinamide.

Question 20

Associated with G6PD deficiency

Answer 20

Suflo