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Biochem PLE | Des > Lipids > Flashcards

Lipids Flashcards

1
Q

Fatty acids are stored as

A

TRIACYLGLYCEROL

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2
Q

Enzyme in DHAP (glycolysis)

A

Glycerol-3 phosphate dehydrogenase

In liver & tissue

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3
Q

Enzyme in phosphorylation of free glycerol

A

Glycerol kinase

Liver ONLY

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4
Q

Enzyme?

Triacylglycerol -> glycerol + 3 FAs

A

Hormone-sensitive lipase

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5
Q

Mobilization of stored fats is activated by

A

Glucagon and epinephrine

Phosphorylation

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6
Q

Mobilization of stored fats is inhibited by

A

Insulin

Dephosphorylation

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7
Q

Beta oxidation occurs in

A

Muscle and liver
FA activation - cytosol
B oxidation - mitochondria

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8
Q

Rate limiting step in beta oxidation

A

Translocation of fatty acyl coA

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9
Q

Enzyme in translocation of fatty acyl coA from cytosol to mitochondria

A

Carnitine-palmitoyl transferase

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10
Q

ATP yield of palmitate

A

106

Nadh 17.5
Fadh 10.5
Acetyl coA 80
Activation -2
106 atp
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11
Q

ATP of 1 NADH

A

2,5

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12
Q

ATP of FADH

A

1.5

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13
Q

Propionyl CoA requires

A

Biotin

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14
Q

Methymalonyl CoA mutase requires

A

Vit B12

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15
Q

Oxidize very long chain of FA

A

Peroxisomes

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16
Q

RL enzyme of lipogenesis

A

Acetly coA carboxylase

17
Q

RL enzyme of beta oxidation

A

Carnitine palmitoyl transferase

18
Q

Location of lipogenesis

A

Cytosol

19
Q

Location of Beta oxidation

A

Mitochondria

20
Q

Citrate shuttle

A

Lipogenesis

21
Q

Carnitine shuttle

A

Beta oidation

22
Q

Condensation
Reduction
Dehydration
Reduction

A

Lipogenesis

23
Q

Repetitive steps in Beta oxidation

A

OHOT

Oxidation
Hydration
Oxidation
THIOLYSIS

24
Q

Product of lipogenesis

A

Palmitate

25
Q

Product of beta oxidation

A

Acetyl coA
NADH
FADH2

26
Q

Inhibitor of lipogenesis

A

Long chain fatty acly CoA

27
Q

Inhibitor of Beta oxidation

A

Malonyl CoA

Biochem PLE | Des (5 decks)

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