Lipids Flashcards

1
Q

Adsorbs cholesterol, lowers LDL

A

Fiber

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2
Q

increases TGs clearance, decreases VLDL

A

Omega 3 Fatty Acids

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3
Q

Statin (lipophilic)

A

Atorvastatin (CYP3A4) (admin anytime)

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4
Q

Statin (hydrophilic)

A

Pravastatin (sulfation, not P450) (admin at night) (urine unchanged)

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5
Q

Absorption blocker

A

Ezetimibe (not P450)(active metabolites)

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6
Q

bile acid sequestrant/resin

A

Cholestyramine (adjunct with statins)(might raise TGs)(upregs reductase)

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7
Q

Increases HDL

A

Niacin (Vitamin B3)(decreases LDL/TGs)

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8
Q

decreases TGs

A

Gemfibrozil (inhibits CYPs) (CI:renal/hepatic dysfunction)

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9
Q

PCSK9 inhibitor

A

Evolocumab

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