Lipids Flashcards
1
Q
essential f.a.
A
linoleic 6(forms arachdonic acid) linolenic 3
2
Q
malic enzyme significance
A
converts malate to pyruvate (goes in mito to transport additional acetyl CoA)
source of NADPH in liver and adipose other than HMP
3
Q
destauration enz cant introduce double bond beyond 9 position
true/false
A
true
4
Q
glycerol kinase
A
source of glycerol 3 P in liver only
liver and adipose:glycolysis
5
Q
apoproteins on lipoproteins
A
chylomicron:apo48
VLDL :apo100
both above have apoCII and apo E
VDL:apo 100
HDL: apoA1 (apoE and apoCII only for giving)
6
Q
statins are comp or non comp inhibitor of HMGCo a reductase
A
competitive
7
Q
how does niacin acts as lipid lowereing drug
A
inhibits hormone sensitivr lipase
dec vldl and then ldl
8
Q
fabry ds is exception in other spingolipidosis as
A
it is XLinked
rest AR
9
Q
features of fabry’s disease
A
febrile ds angiokeratomas/a galactosidase def burning pain(peripheral neuropathy) renal failure youth death ceramide trihexoside cardiovascular ds
