Lipids Flashcards

0
Q

Primary source of fuel

A

Lipids

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1
Q

Commonly referred to as fats

A

Lipids

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2
Q

Conjugated lipids

A

Phospholipids

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3
Q

Most abundant lipids are derived from where?

A

Phosphatidic acid

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4
Q

Formed by the conjugation of two fatty acids and a phosphorylated glycerol

A

Phospholipids

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5
Q

Only phospholipid not derived from glycerol

A

Sphingomyelin

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6
Q

Sphingomyelin is derived from an amino alcohol called __________

A

Sphingosine

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7
Q

Sphingomyelin accumulates in the liver and spleen of patients suffering from what?

A

Niemann-Pick disease

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8
Q

Unsaturated steroid alcohol containing four rings and has a single C-H side chain tail similar to fatty acids

A

Cholesterol

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9
Q

True or False: Cholesterol serves as a source of fuel

A

False

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10
Q

Transport and excretion of cholesterol is promoted by what hormone?

A

Estrogen

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11
Q

Precursor of five major classes of steroids

A

Cholesterol

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12
Q

Cholesterol bound to fatty acid (hydrophobic form)

A

Cholesterol ester

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13
Q

Catalyzes the eterification of cholesterol by promoting the transfer of fatty acids from lecithin to cholesterol

A

Lecithin-Cholesterol Acyl Transferase (LCAT)

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14
Q

Activator of LCAT

A

Apo A-1

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15
Q

Polar nonesterified form of alcohol

A

Free cholesterol

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16
Q

Linear chains of carbon-hydrogen bonds that terminate with a carboxyl group

A

Fatty acids

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17
Q

Provide substance for conversion to glucose (gluconeogenesis)

A

Fatty acids

18
Q

Enzyme that hydrolyzes TAG in lipoproteins and release of fatty acid and glycerol

A

Lipoprotein lipase

19
Q

Enzyme that hydrolyzes TAG and phospholipids from HDL

A

Hepatic lipase

20
Q

Enzyme that hydrolyzes lipids on VLDL and IDL

A

Hepatic lipase

21
Q

Catalyzes the esterification of cholesterol from HDL

A

LCAT

22
Q

Enables HDL to accumulate cholesterol as cholesterol ester

A

LCAT

23
Q

Hydrolyzes phospholipids and TAG in HDL

A

Endothelial lipase

24
Q

Its main purpose is to transport TAG and cholesterol to sites of energy storage and utilization

A

Lipoproteins

25
Q

Largest and least dense of the lipoprotein particles

A

Chylomicrons

26
Q

Where are chylomicrons produced?

A

Intestine

27
Q

Transports exogenous/dietary TAG to liver, muscles and fat depot

A

Chylomicrons

28
Q

Which organ secretes VLDL?

A

Liver

29
Q

Transports expgenous TAG from liver to muscle, fat depots and peripheral tissues

A

VLDL

30
Q

Smallest lipoprotein and least dense

A

HDL

31
Q

Alpha lipoprotein

A

HDL

32
Q

Pre-beta lipoprotein

A

VLDL

33
Q

Beta lipoprotein

A

LDL

34
Q

Major end product resulting from the catabolism of VLDL

A

LDL

35
Q

Most cholesterol-rich lipoprotein

A

LDL

36
Q

Product of VLDL catabolism

A

Intermediate density lipoprotein (IDL)

37
Q

Electrophoretic pattern of lipoproteins

A

HDL, VLDL, LDL, Chylomicrons

38
Q

Subclass of LDL

A

IDL

39
Q

“Sinking pre-B lipoprotein”

A

Lipoprotein a

40
Q

Abnormal lpp found in obstructive jaundice and LCAT deficiency

A

Lipoprotein X

41
Q

“Abnormally migrating B-VLDL”

A

B-VLDL/floating B-lpp

42
Q

Reference mtd for the quantitation of lpp

A

Ultracentrifugation