Lipids Flashcards
a family of substances found in living organisms that are insoluble in water but soluble in nonpolar solvents and solvents of low polarity
Lipids
Lipids play three major roles in human biochemistry:
- they store energy within fat cells.
- they are parts of membranes that separate compartments of aqueous solutions from each other, and
- they serve as chemical messengers.
Lipids can be classified into four groups:
- simple lipids such as fats and waxes;
- complex lipids;
- steroids; and
- prostaglandins, thromboxanes, and leukotnenes.
consist of a hydrocarbon chain with a carboxylic acid at one end
Fatty acid
2-4 carbon atoms
short chain FA
6-10 carbon atoms.
medium chain FA
12 - 26 carbon atoms
long chain FA
are two examples of essential fatty acid
linoleic and linolenic
Is a ubiquitous component of plant lipids and of all the seed oils of commercial importance.
Linoleic acid
is thought to decrease the risk of heart disease by helping to maintain noral heart thythin and pumping it might also redure blood clots:
Linolenic acids
Polyunsaturated fatty acids occur in higher concentration in lipids associated with structural elements of tissues.
Structural elements of tissues
Lipids of gonads also contain a high concentration of polyunsaturated fatty acids, which suggests importance of these compounds in reproductive function.
Structural element of gonads
Prostaglandins are synthesised from Arachidonic acid by cyclooxygenase enzyme system. Leucotrienes are conjugated trienes formed from arachidonic acid in. leucocytes by the Lipoxygenase pathway.
Synthesis of prostaglandins and other compounds
A deficiency of EFA causes swelling of mitochondrial membrane and reduction in efficiency of oxidative phosphorylation. This may explain for increased heat production noted in EFA deficient animals.
Structural element of mitochondrial membrane
Fats with high content of polyunsaturated fatty acids tends to lower serum level of cholesterol.
strum level or cholesterol
Prolongation of clotting time is noted in ingestion of fats rich in EFA.
Effect on clotting time