Lipids Flashcards
Which Frederickson type is associated with high LDL and
normal triglyceride?
a. Type III
b. Type IIa
c. Type I
d. Type IIb
b. Type IIa
What is the function of Apo B 100 in lipid metabolism?
a. Facilitate the entry of chylomicrons in the lymphatic circulation
b. Activate LPL in the tissues
c. Activate Lipolysis of Triglycerides
d. Serve as ligand for LDL entry inside peripheral cells
d. Serve as ligand for LDL entry inside peripheral cells
THEY SERVE TO TRANSPORT ENDOGENOUSLY. SYNTHESIZED LIPIDS, MAINLY TRIGLYCERIDES (BUT ALSO SOME CHOLESTEROL AND CHOLESTERYL ESTERS) TO PERIPHERAL TISSUES. VLDL IS A LSO THE PRECURSOR OF LDL. APOB100 IS ABSOLUTELY REQUIRED FOR VLDL ASSEMBLY AND SECRETION.
Deficiency of LCAT will affect which metabolic pathways?
a. Stimulate the entry of LDL into the cell
b. Decreased production of chylomicrons
c. Decreased production of the mature forms of HDL
d. Stimulates the lipolysis of Triglycerides
c. Decreased production of the mature forms of HDL
APOA1 ACTIVATES LCAT TO CONVERT NASCENT HDL TO MATURE HDL.
Which of the following factors will cause an increase in cholesterol level?
a. Winter time
b. High intake of ascorbic acid
c. Childbirth
d. Increasing age
b. High intake of ascorbic acid
HIGHER DOSE, SHORTER DURATION AND OLDER AGE,
VITAMIN C SUPPLEMENTATION SIGNIFICANTLY INCREASED LDL LEVEL
Which lipoproteins take cholesterol from the periphery
to the liver?
a. HDL
b. LDL 3
c. LDL 2
d. VLDL
a. HDL
| LDL TAKES CHOLESTEROL FROM LIVER TO PERIPHERY
HDL TAKES CHOLESTEROL FROM PERIPHERY TO LIVER
Which of the following is FALSE about lipoproteins?
a. HDL has more proteins than triglycerides
b. VLDL has more triglycerides than LDL
c. LDL is derived from IDL
d. Small particle LDL is more cardioprotective
than the large LDL
d. Small particle LDL is more cardioprotective
than the large LDL
| SMALL, DENSE LDL PARTICLES ARE MORE ATHEROGENIC
THAN LARGE, BUOYANT LDL PARTICLES, AND OXIDATION
OF LDL ALSO INCREASES ITS ATHEROGENICITY.
Which of the following is NOT a component of the surface
of the lipoproteins?
a. Cholesterol
b. Phospholipids
c. Cholesterol ester
d. Apoproteins
c. Cholesterol ester
Which of the following is NOT a criterion for the diagnosis
of Metabolic Syndrome?
a. Obesity
b. Hypertension
c. Sudden weight loss of more than 20 lbs
d. Hyperglycemia
c. Sudden weight loss of more than 20 lbs
What is the role of Apo C – II?
a. Carry chylomicrons inside the liver
b. Split VLDL to IDL
c. Activates pancreatic lipase
d. Activates lipoprotein lipase
d. Activates lipoprotein lipase
|
What is the effect on the lipid level if blood is collected
on patient in recumbent position for more than 30
minutes?
a. Increased chylomicrons
b. Increased cholesterol and triglycerides
c. Increased HDL and lower LDL
d. Decreased triglycerides and cholesterol
d. Decreased triglycerides and cholesterol
| THESE FINDINGS CAN BE FULLY EXPLAINED BY DECREASE
IN PLASMA VOLUME ON CHANGING F ROM LYING TO THE
ERECT POSITION.
