LipidChem Flashcards

1
Q

Classification of lipids

A

siple lipids, complex lipids and precursor and derived lipids

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2
Q

simple lipids are made up of

A

esters of fatty acids + alcohols

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3
Q

Classifications of simple lipids

A

Fats and Waxes

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4
Q

main storage form of fats

A

Triacylglycerol

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5
Q

Classification of Simple lipids where in esters of fatty acids with higher molecular weight monohydric alcohol. A hdroxy group and a carboxyl group give rise to ester bond

A

Waxes

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6
Q

Classification of Lipids where in esters of fatty acids containing groups in addition to an alcohol and a fatty acid

A

Complex Lipids

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7
Q

Phospholipid is composed of ____

A

Fatty acid + Alcohol + Phosphoric Acid

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8
Q

Glycerophospholipid is composed of _____

A

Fatty acid + Glycerol + Phosphoric Acid

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9
Q

Sphingophospholipid is composed of ____

A

Fatty acid + Sphingosine + Phosphoric Acid

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10
Q

Glyceroglycolipids and Sphingoglycolipids are examples of _____

A

Glycolipids

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11
Q

Two divisions of sphingoglycolipids

A

Cerebroside and Ganglioside

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12
Q

Activated form of fatty acids on glcyerophospholipids are attached to what carbon numbers?

A

C1 and C2

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13
Q

What is attached to the 3rd Carbon atom of a Glycerophospholipid?

A

Phosphate Ester

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14
Q

Where can you find phophatidylethonolamine

A

Cell membrane

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15
Q

What is the other name for phosphatidylethonolamine

A

Cephaline

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16
Q

What is the most abundant phopsholipid in the cell membrane?

A

Phosphatidylcholine

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17
Q

What is Phosphatidylcholine’s also known as?

A

Lecithin

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18
Q

What phospholipid is a major constituent of pulmonary surfactant?

A

Phosphatidylcholine—dipalmitoyl Lecithin

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19
Q

The structural basis of the 2nd messenger of hormones (PIP2)

A

Phosphatidylinositol

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20
Q

enzyme that acts on Phosphatidylinositol 4,5-bisphosphate to form Diacylglycerol and Inositol triphosphate

A

Phospholipase C

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21
Q

2nd messenger products of phosphatidylinositol 4,5 bisphosphate

A

Diacylglycerol and Inositol Triphosphate

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22
Q

A phosphatidylglycerol that can be found only in the inner mitochondrial membrane that serves as a proton trap in oxidative phosphorylation

A

Cardiolipin (diphosphatidyl glycerol)

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23
Q

What is the other phospholipid other than Phosphatidylcohline that can be found in pulmonary surfactant

A

phosphatidylglycerol

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24
Q

What is the base of Sphingomyelin

A

Choline

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25
Q

Site and function of Sphingomyelin

A

Found in the myelin sheath and is important for cell signaling pathways

26
Q

Difference between Glycerophospholipid and Sphingophospholipid

A

Sphingophospholipid has 1 FA and 1 Phosphate Ester; Glycerophospholipid has 2 FA and 1 Phosphate ester

27
Q

Glycolipids are composed of

A

FA + Alcohol + Carbohydrate

28
Q

Glycolipid that is found in weat flour

A

Flyceroglycolipid

29
Q

Disease related B-Galactocerebroside

A

Krabbe’s disease

30
Q

Disease related to B-Glucocerebroside

A

Gaucher’s diease

31
Q

location of B-Galactocerebroside

A

Brain and myelin sheath

32
Q

location of B-Glucocerebroside

A

Liver and spleen

33
Q

A Sphingosine + FA is a ____

A

Ceramide

34
Q

Glucose + Galactose + ceramide

A

GM3

35
Q

GluGal + NacetylD-galactosamine

A

GM2

36
Q

Glucose + Galactose + NAcetylD-galactosamine + Galactose

A

GM1

37
Q

Enzyme related to Gangliosidosis

A

GM1-B-galactosidase

38
Q

Disease related to hexaminidase A

A

Tasy Sach’s disease

39
Q

Deficiency of Sulfolipid is associated with what?

A

Matachromatic leukodystrophy

40
Q

Apoliproprotein in LDL

A

B100

41
Q

Lipoprotein with B-48

A

Chylomicron

42
Q

Lipoprotein with D

A

HDL

43
Q

Carries exogenous TAG

A

Chylomicrons (B48)

44
Q

representing a final stage in the catabolism of VLDL

A

LDL

45
Q

derived from the liver for the export of triacylglycerol

A

VLDL

46
Q

involved in cholesterol transport and VLDL and chylomicron metab

A

HDL

47
Q

C atoms in a short Chain

A

2-4C

48
Q

C atoms in a medium Chain

A

6-12C

49
Q

C atoms in a Long chain

A

More than 12 C

50
Q

The adjacent hydrogen group is at the same side of the double bond

A

Cis

51
Q

The hydrogen group is at the opposite side of the double bound

A

Trans

52
Q

why is B-hydroxybutyric acid not a real true ketone body

A

carbony carbon not attached to carbon instead to a carboxyl group

53
Q

Vitamin for visual pigment

A

A

54
Q

Vitamin for metabolism and growth

A

D

55
Q

Vitamin for antioxidation

A

E

56
Q

Vitamin for blood clotting factor

A

K

57
Q

Pathway of lipid digestion

A

Stomach (lingual and gastric lipase) -> Duodenum -> Pancreatic lipase -> Intestinal lumen -> Liver

58
Q

fates of glycerol

A

portal vein and phosphatidic acid pathway

59
Q

Fates of Fatty Acid

A

heaptic portal vein as free fatty acid and triacylglcerol -> chylomicrons -> thoracic duct

60
Q

Digestive Products

A

Free FA + 2monoacylglycerol + Cholesterol + Free FA